Abstract：Objective To study the effect and bleeding risk of titanium clips in endoscopic mucosal resection (EMR) of colorectal polyps. Methods From January 2018 to December 2019, 50 patients with colonic and rectal polyps who admitted to the Department of Gastroenterology, the First People′s Hospital of Chuzhou were selected as the study objects. They were divided into the observation group and the control group according to the random number table method, with 25 cases in each group. Routine EMR was performed in the control group, while titanium clip was used in the observation group on the basis of the control group. The operation time, intraoperative bleeding volume, recovery time of bowel sounds, visual analogue scale (VAS) score of defecation pain, score of defecation difficulty, secondary operation rate and complications during hospitalization were compared between the two groups. The levels of cortisol (COR), adrenaline (E), noradrenaline (NE) and dopamine (DA) were compared before and 12 h after operation. Results The amount of bleeding, VAS score and the number of secondary operations in the observation group were significantly lower than those in the control group (P ＜ 0.05). Compared with pre-operation, the postoperative COR, E, NE and DA of the two groups were increased, and the difference was statistically significant (P ＜ 0.05). There was no statistically significant difference in COR, E, DA between the two groups (P ＞ 0.05). The postoperative NE of the observation group was lower than that of the control group, and the difference was statistically significant (P ＜ 0.05). The incidence of bleeding and complications in the observation group were significantly lower than those in the control group, and the differences were statistically significant (all P ＜ 0.05). Conclusion The application of titanium clip in EMR of colon and rectum polyp can reduce the risk of bleeding and the incidence of postoperative complications.
2020, Vol. 17 
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