Effect of early diuretic combined with enhanced recovery after surgery on postoperative recovery of colon and rectal cancer patients
MA Nan1 MA Shanxin2 LI Yan1 LIN Weishan2 TAO Guanglin2
1.Department of General Surgery, Dongying District People′s Hospital, Shandong Province, Dongying 257000, China;
2.Department of Rehabilitation Medicine, the First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning 530021, China
Abstract：Objective To investigate the effect of early diuretic injection therapy combined with enhanced recovery after surgery (ERAS) on colon and rectal cancer after elective surgery. Methods A total of 214 patients who received elective surgery for colon and rectal cancer from January 2017 to December 2018 in Dongying District People′s Hospital of Dongying City in Shandong Province, were randomly divided into the intervention group and the control group according to the random number table method, with 107 patients in each group. The intervention group was treated with intravenous furosemide 10 mg on day 1 and day 2 after surgery and combined with ERAS, and the control group was treated with ERAS intervention alone. The hospital stay, readmission rate within 30 days, defecation time, weight change and incidence of complications were compared between the two groups after surgery. Results There was no statistically significant difference in length of hospital stay, readmission rate within 30 days, and weight change between the two groups after surgery (P ＞ 0.05). Defecation time in the intervention group after surgery was significantly longer than that in the control group, and the difference was statistically significant (P ＜ 0.05). There was no statistically significant difference in the incidence of acute renal injury, hypokalemia, CT drainage needed for abscess, wound infection, reentry surgery, and intestinal obstruction between the two groups after surgery (P ＞ 0.05). Conclusion Early use of furoxime diuretics combined with ERAS is not conducive to postoperative recovery of colon and rectal cancer patients.
马楠1 马善新2 李燕1 林伟山2 陶广林2. 早期利尿联合加速康复外科理念对结、直肠癌患者术后恢复的影响[J]. 中国医药导报, 2020, 17(11): 98-101.
MA Nan1 MA Shanxin2 LI Yan1 LIN Weishan2 TAO Guanglin2. Effect of early diuretic combined with enhanced recovery after surgery on postoperative recovery of colon and rectal cancer patients. 中国医药导报, 2020, 17(11): 98-101.
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2020, Vol. 17 
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