Abstract：Objective To observe the clinical effect of hyperthermia combined with radiotherapy and chemotherapy in the treatment of locally advanced non-small cell lung cancer (NSCLC) and its effect on survival. Methods A total of 110 patients with locally advanced NSCLC admitted to the Chemoradiot Department of Tangshan People′s Hospital from January 2015 to January 2017 were selected. They were divided into the observation group and the control group by random number table method, with 55 cases in each group. The observation group received synchronous radiotherapy and chemotherapy combined with hyperthermia, and the control group received synchronous radiotherapy and chemotherapy. The short-term efficacy, incidence of toxic and side effects and long-term survival of the two groups were compared. Results The effective rate of the observation group was significantly higher than that of the control group, and the difference was statistically significant (P ＜ 0.05). There was no statistically significant difference in the incidence of radiation esophagitis, radiation pneumonia, myelosuppression and radiation dermatitis between the two groups (P ＞ 0.05). The 2-year cumulative survival rate of the observation group was higher than that of the control group, and the difference was statistically significant (P ＞ 0.05). Conclusion The short-term efficacy of hyperthermia combined with radiotherapy and chemotherapy in the treatment of locally advanced NSCLC is accurate, and the survival rate is improved compared with that of radiotherapy and chemotherapy alone.
赵凯 王志武 杨俊泉. 热疗联合放化疗治疗局部晚期非小细胞肺癌的临床效果[J]. 中国医药导报, 2020, 17(11): 84-87.
ZHAO Kai WANG Zhiwu YANG Junquan. Clinical effect of hyperthermia combined with chemoradiotherapy in the treatment of locally advanced non-small cell lung cancer. 中国医药导报, 2020, 17(11): 84-87.
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2020, Vol. 17 
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