Abstract：Objective To explore the effect of cluster nursing on quality of life and psychological burden of patients with multiple myeloma. Methods From February 2017 to February 2018, 104 myeloma patients who admitted to the department of Hematology, The Third Hospital of Hebei Medical University were selected. According to the random number table method, all the patients were divided into the control group and the observation group, with 52 cases in each group. The control group received routine nursing, and the observation group received cluster nursing on the basis of the control group. The two groups were compared in terms of psychological burden, pain, toxic and side effects, coagulation indexes and quality of life. Results After intervention, the self-rating anxiety scale scores and self-rating depression scale scores of the two groups were significantly reduced than those befere intervention, and the scores of the observation group were significantly lower than those of the control group (P ＜ 0.05). The level of coagulation index in both groups was lower than that before the intervention, and the observation group was lower than the control group (P < 0.05). During chemotherapy, the observation group level of pain during chemotherapy was mild and the proportion of the toxic and side reaction Ⅰ-Ⅱ magnitude ratio are higher than the control group (all P ＜ 0.05). Conclusion For patients with myeloma, cluster nursing can alleviate anxiety and depression, alleviate psychological burden of patients, alleviate pain, reduce toxic and side effects of chemotherapy, and improve the quality of life of patients.
孙秀梅 徐红艳 李彩会 于金花. 集束化护理对骨髓瘤患者生存质量及心理负担的影响[J]. 中国医药导报, 2020, 17(10): 181-184.
SUN Xiumei XU Hongyan LI Caihui YU Jinhua. Effect of cluster nursing on quality of life and psychological burden of myeloma patients. 中国医药导报, 2020, 17(10): 181-184.
[1] Iida S，Shimazaki C，Abe M，et al. JSH practical guidelines for hematological malignancies，2018：Ⅲ. Myeloma-2. Related disorders of multiple myeloma [J]. Int J Hematol，2019，109（6）：633-640.
[2] Sævareid TJL，Lillemoen L，Thoresen L，et al. Implementing advance care planning in nursinghomes-study protocol of a cluster-randomized clinical trial [J]. BMC geriatrics，2018，18（1）：180.
[3] 陈明燕.集束化护理对慢性阻塞性肺疾病患者肺通气功能及生活质量的影响[J].检验医学与临床，2017，14（12）：1830-1833.
[4] 任金新.循证护理在多发性骨髓瘤患者疼痛管理的应用[J].中西医结合心血管病电子杂志，2019，7（10）：135.
[5] 杨丽萍.多发性骨髓瘤患者护理中循证理念的运用意义研究[J].实用临床护理学电子杂志，2018，3（16）：148-155.
[6] 王慧芳.集束化护理对多发性骨髓瘤疼痛的影响[J].护理实践与研究，2018，15（18）：110-112.
[7] Delanghe J，Speeckaert R，Marijn M，et al. Albumin assays and clinical decision-making in nephrotic syndrome patients [J]. Kidney International，2019，96（1）：248-249.
[8] Kim K，Lee JH，Kim JS，et al. Clinical Profiles of Multiple Myeloma in Asia-an Asian Myeloma Network Study [J]. Am J Hematol，2014，89（7）：751-756.
[9] 刘佳璋，黎桂花，欧阳春兰.循证护理在多发性骨髓瘤患者疼痛管理的应用[J].护理实践与研究，2017，14（8）：97-99.
[10] Zhang Y，Muyiduli X，Wang S，et al. Prevalence and relevant factors of anxiety and depression among pregnant women in a cohort study from south-east China [J]. J Reprod Infant Psyc，2018，36（5）：519-529.
[11] 温艳君.整体干预模式在多发性骨髓瘤治疗中对生活质量和凝血指标的影响[J].血栓与止血学，2018，24（4）：696-698.
[12] 赖玲.循证护理在预防多发性骨髓瘤的毒副反应中的效果观察[J].实用临床医药杂志，2017，21（16）：24-26.
[13] van Delft-Schreurs CCHM，van Son MAC，de Jongh MAC，et al. The relationship between physical and psychological complaints and quality of life in severely injured patients [J]. Injury，2017，48（9）：1978-1984.
[14] Terpos E. Multiple Myeloma：Clinical updates from the american society of hematology annual meeting，2017 [J]. Clin Lymphoma Myeloma Leuk，2017，17（6）：329-339.
[15] 颜敏超，曾惠，李园，等.多发性骨髓瘤合并HBV感染的临床分析[J].中华医院感染学杂志，2017，27（24）：5646-5649.
[16] 唐小丽，张婷，杨慧，等．四川省55所二级甲等及以上医院癌痛规范化护理的现状分析[J].中华护理杂志，2016，51（4）：424-428.
[17] 孙博玮，傅荣，褚红，等.144例多发性骨髓瘤患者心理弹性现状及影响因素分析[J].护理学报，2019，26（10）：38-43.
[18] 刘梅，高晓艳.棚替佐米方案诱导治疗对多发性骨髓瘤患者凝血四项及血栓相关事件发生率的影响[J].血栓与止血学，2017，23（2）：250-252.
[19] 袁敏，余晓云，温雅婷，等.集束化护理在晚期癌痛规范化治疗中的应用研究[J].重庆医学，2017，46（28）：4023-4025.
[20] 王晓雪，张贺洋，潘登，等.初诊多发性骨髓瘤患者凝血指标的变化及意义[J].中国全科医学，2014，17（15）：1773-1775.
[21] 张彦，李丽，高丹，等.多发性骨髓瘤继发骨髓纤维化的骨髓病理学特征及与疾病预后的关系评价[J].中国现代医生，2019，57（19）：10-13.
[22] 黄亚丽，马占忠，黄刚，等.多发性骨髓瘤患者骨髓细胞中CD269、CD317的表达及其意义[J].中国医药导报，2019，16（13）：103-106.
2020, Vol. 17 
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