Abstract：Objective To study the clinical value of breast MRI and axillary ultrasonography in the differential diagnosis of axillary lymph node metastasis in breast cancer patients. Methods The data of 229 patients with breast cancer underwent radical mastectomy, modified radical mastectomy or radical mastectomy in Xuanwu Hospital from October 2016 to September 2017 were retrospectively analyzed. All patients underwent preoperative MRI and axillary ultrasound examination, underwent radical mastectomy and axillary lymph node dissection, and underwent routine pathological examination of lymph nodes. The correlation between MRI and axillary ultrasound findings and postoperative pathological findings were observed. Results Axillary lymph node metastasis was detected in 102 of 229 patients, and no metastasis was detected in 127 patients. 108 cases of axillary lymph node metastasis were detected by MRI, of which 91 cases were consistent with the cases, 17 cases were misdiagnosed, and 11 cases were missed. Axillary lymph node metastasis was detected in 98 cases by ultrasound, 80 cases were consistent with pathological diagnosis, 18 cases were misdiagnosed, and 22 cases were missed diagnosis. The sensitive of MRI in diagnosis of axillary lymph node metastasis was higher than that of axillary ultrasound, with statistically significant difference (P < 0.05). There was significant difference in specificity and accuracy of diagnosis between MRI and axillary ultrasound (P > 0.05). The specificity of MRI positive and axillary ultrasound positive in diagnosis of axillary lymph node metastasis was higher than that of MRI, axillary ultrasound and MRI positive or axillary ultrasound positive (P ＜ 0.05). The sensitivity of MRI positive or axillary ultrasound positive was higher than that of MRI, axillary ultrasound, MRI positive and axillary ultrasound positive (P ＜ 0.05). Conclusion The breast MRI and axillary ultrasonography are important means of detecting lymph node metastasis in breast cancer, both positive is helpful for the diagnosis of axillary lymph node metastasis, one positive in the two indicator is helpful for the diagnosis of axillary lymph node metastasis, clinical can flexibly according to the actual situation.
杜岚 杨敬春▲ 常莹. 标准乳腺MRI与腋窝超声鉴别乳腺癌有无转移及晚期腋窝淋巴结病变的差异[J]. 中国医药导报, 2017, 14(35): 168-171.
DU Lan YANG Jingchun▲ CHANG Ying. Comparison of diagnostic value of breast MRI and ultrasonography in axillary lymph node metastasis of breast cancer. 中国医药导报, 2017, 14(35): 168-171.
2017, Vol. 14 
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