Analysis methods and utilization of clinical medical data
YAO Chunxu1 JI Chengdong2▲ FU Qiangqiang2 LI Shuman2
1.Central laboratory, Central Hospital of Shanghai Yangpu District, Yangpu Hospital of Tongji University, Shanghai 200090, China;
2.Research management department, Central Hospital of Shanghai Yangpu District, Yangpu Hospital of Tongji University, Shanghai 200090, China
Abstract:Based on the theory of the evidence-based medicine, the relevant information of the topic “analysis and utilization of clinical data” was searched. Sinomed, Wanfang Data, VIP and Chinese National Knowledge Infrastructure databases were searched to comprehensively collect related articles. The paper elaborates the following aspects: the data processing, the statistical analysis and utilization of the clinical data in the medical field as well as the confronting problems, in order to provide some references about clinical data management in the forthcoming years for big medical data.
姚纯旭1 嵇承栋2▲ 付强强2 李舒曼2. 临床医学数据的分析方法与利用[J]. 中国医药导报, 2017, 14(35): 163-167.
YAO Chunxu1 JI Chengdong2▲ FU Qiangqiang2 LI Shuman2. Analysis methods and utilization of clinical medical data. 中国医药导报, 2017, 14(35): 163-167.
[1] 谢高强.数据管理在临床研究中的地位和作用[J].北京大学学报:医学版,2010,6(42):641-643.
[2] 国家药品监督管理局.药品临床试验管理规范[J].中国新药杂志,1999,8(11):422-426.
[3] 国家食品药物监督管理局.药物临床试验质量管理规范[J].中国医药导刊,2003,5(5):367-372.
[4] 魏婉.关于促进和规范健康医疗大数据应用发展的指导意见[J].科研,2016,(9):306-307.
[5] 屈景辉,廖琪梅,许卫中,等.医学信息数据库的建立与数据挖掘[J].医学争鸣,2001,22(1):88-89.
[6] 李志刚,朱志军.大数据时代:生活、工作与思维的大变革[J].西域图书馆论坛,2013(1):213-213.
[7] 刘柏嵩.基于知识的语义网:概念、技术及挑战[J].中国图书馆学,2003,29(2):18-21.
[8] 马惠芳.非结构化数据采集和检索技术的研究和应用[D].上海:东华大学,2013.
[9] 李维.基于大数据技术的临床数据中心与智能分析应用平台构建[J].医学信息学杂志,2014,35(6):13-17.
[10] 王禹毅,韩梅,陈妮妮,等.从如何获得高质量临床数据探讨临床试验的数据管理[C]//中医/中西医结合循证医学方法研讨会会议材料.2013.
[11] 杨海青.数据挖掘技术在医院管理中的应用[J].中华医院管理杂志,2005,21(7):497-499.
[12] 庞璋帆,罗震钧,定天明,等.基于神经网络算法的药品安全指数权值策略研究[J].医药前沿,2016,6(1):370-371.
[13] 刘昆,刘业政.基于决策树的医疗数据分析[J].计算机工程,2002,28(2):41-43.
[14] 方匡南,吴见彬,朱建平,等.随机森林方法研究综述[J].统计与信息论坛,2011,26(3):32-38.
[15] 张学工.关于统计学习理论与支持向量机[J].自动化学报,2000,26(1):32-42.
[16] 杜喆.几类支持向量机变型算法的研究[D].西安:西安电子科技大学,2009.
[17] 黄宏兴,柴生颋,黄红,等.骨质疏松症中医证型的聚类分析[J].广州中医药大学学报,2007,24(3):180-183.
[18] 毛勇,周晓波,夏铮,等.特征选择算法研究综述[J].模式识别与人工智能,2007,20(2):211-218.
[19] Tsoukalas LH,Uhrig RE,Zadeh LA. Fuzzy and neural approaches in engineering[C]// John Wiley & Sons,Inc.1997.
[20] 俞梦孙.关于我国医学信息技术的发展[J].中国生物医学工程学报,2008,27(2):161-163.
[21] Ginsberg J,Mohebbi MH,Patel RS,et al. Detecting influenza epidemics using search engine query data [J]. Nature,2009,457(7232):1012-1014.
[22] 陶御风,袁久林,梁慧凤,等.浅谈古方筛选利用的思路与方法[J].上海中医药杂志,2005,39(5):42-43.
[23] 刘晓,俞志元.美国医院和区域卫生信息化发展及其对中国的借鉴[J].医学信息学杂志,2010,31(5):8-11.
[24] Safran C,Bloomrosen M,Hammond WE,et al. Toward a national framework for the secondary use of health data:an American medical informatics association white paper [J]. J Am Med Inform Assoc,2007,14(1):1-9.
[25] Embi PJ. Clinical research informatics:survey of recent advances and trends in a maturing field [J]. Yearb Med Inform,2013,8(1):178.
[26] Shmueliblumberg D,Hu L,Allen C,et al. The national drug abuse treatment clinical trials network data share project:website design,usage,challenges,and future directions [J]. Clin Trials,2013,10(6):977-986.
[27] 汪鹏.医疗大数据应用需求分析与平台建设构想[J].中国医院管理,2015,6(35):40-42.
[28] Collins FS,Varmus H. A new initiative on precision medicine [J]. N Engl J Med,2015,372(9):793.
[29] 袁浩.基于临床数据中心的循证知识管理模式分析[J].医学信息学杂志,2015,36(3):7-10.
[30] Lazer D,Kennedy R,King G,et al. Big data. The parable of Google Flu:traps in big data analysis [J]. Science,2014, 343(6176):1203-1205.