Systematic evaluation of the quality of clinical treatment guidelines for hypertension in children and adolescents
DING Xiangyu1 WANG Jianxin2 FENG Chao1 ZHANG Guying1
1.Department of Pharmacy, Hebei Children′s Hospital, Hebei Province, Shijiazhuang 050031, China;
2.Department of Pharmacy, the First Hospital of Hebei Medical University, Hebei Province, Shijiazhuang 050030, China
Abstract：Objective To systematically review the methodological quality guidelines on the hypertension guidelines in children and adolescents, to compare the recommendations and to provide a reference for clinical physicians and pharmacists. Methods CNKI, Wanfang Database, VIP, CBM, PubMed, Excerpta medica database (EMBASE) and relevant websites such as medlive.cn, guideline international network (GIN), American academy of pediatrics (AAP), national guideline clearinghouse (NGC), national institute for health and clinical excellence (NICE) were searched by computer ranged from inception to October 2018. The methodological quality of included guidelines were evaluated according to the appraisal of guidelines for research and evaluationⅡ (AGREEⅡ) instrument, and the differences between recommendations were compared. Results The three guidelines are from the European socienty of hypertension (ESH), American academy of pediatrics (AAP), Canadian hypertension education program (CHEP), respectively. In the six major areas of the AGREEⅡ system, only the “clearness” and “range and purpose” scores were high. The AAP and CHEP guidelines were level B, and the ESH guidelines was level C. The recommended treatment recommendations of the guidelines are basically the same. Conclusion The quality of the included guidelines needs to be further improved. In the future development of guidelines for hypertension in children and adolescents, rigor of development and applicability of the guidelines should be strengthened. It is better to use evidence-based evaluation to obtain high-quality guidelines, so as to provide the best evidence for clinical treatment of hypertension in children.
丁翔宇1 王建欣2 冯超1 张古英1. 儿童青少年高血压临床治疗指南质量的系统性评价[J]. 中国医药导报, 2020, 17(6): 73-76.
DING Xiangyu1 WANG Jianxin2 FENG Chao1 ZHANG Guying1. Systematic evaluation of the quality of clinical treatment guidelines for hypertension in children and adolescents. 中国医药导报, 2020, 17(6): 73-76.
[1] 国家心血管病中心.中国心血管病报告2015[M].北京：中国大百科全书出版社，2016：23-30.
[2] Falkner B，Daniels SR，Flynn JT，et al. Summary of the Fourth Report on the Diagnosis，Evaluation，and Treatment of High Blood Pressure in Children and Adolescents [J]. Hypertension，2004，44（4）：387-388.
[3] Kollias A，Dafni M，Poulidakis E，et al. Out-of-office blood pressure and target organ damage in children and adolescents：a systematic review and meta-analysis [J]. J Hypertens，2014，32（12）：2315-2331.
[4] Gray L，Lee IM，Sesso HD，et al. Blood pressure in early adulthood，hypertension in middle age，and future cardiovascular disease mortality：HAHS（Harvard alumni health study）[J]. J Am Coll Cardiol，2011，58（23）：2396-2403.
[5] 田杰，孙慧超.儿童高血压的临床表现及判断标准[J].中华实用儿科临床杂志，2015，30（13）：968-971.
[6] 李静，苏玉，潘怡，等.天津市城区儿童青少年体质指数和腰围与血压的关系[J].中国慢性病预防与控制，2014， 22（6）：707-709.
[7] 刘志学.儿童青少年高血压：一个亟待重视的问题[J].中国医药导报，2019，9（6）：1-4.
[8] 陈尹，胡世莲，李幼平，等.全球药物干预治疗单纯性高血压指南的系统评价[J].中国循证医学杂志，2012，12（10）：1180-1194.
[9] Zhang ZC，Guo J，Su G，et al. Evaluation of the quality of guidelines for myasthenia gravis with the AGREE Ⅱ Instrument [J]. PLoS One，2014，9（11）：e111796.
[10] 王维，陈青山，刘治民.应用Excel完成组内相关系数ICC的计算和评价[J].中国卫生统计，2008，25（3）：314-315.
[11] Lurbe E，Agabiti-Rosei E，Cruickshank JK，et al. 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents [J]. J Hypertens，2016，34（10）：1887-1920.
[12] Flynn JT，Kaelber DC，Baker-Smith CM，et al. Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents [J]. Pediatrics，2017，140（3）：e20171904
[13] Dionne JM，Harris KC，Benoit G，et al. Hypertension Canada′s 2017 guidelines for the diagnosis，assessment，prevention，and treatment of pediatric hypertension [J]. Can J Cardiol，2017，33（5）：577-585.
[14] Shi Y，Groh M，Morrison H. Increasing blood pressure and its associated factors in Canadian children and adolescents from the Canadian Health Measures Survey [J]. BMC Public Health，2012，12：388.
[15] Ho M，Garnett SP，Baur L，et al. Effectiveness of lifestyle interventions in child obesity：systematic review with meta-analysis [J]. Pediatrics，2012，130（6）：e1647-e1671.
[16] Cai L，Wu Y，Wilson RF，et al. Effect of childhood obesity prevention programs on blood pressure：a systematic review and meta-analysis [J]. Circulation，2014，129（18）：1832-1839.
[17] Sorof JM，Cargo P，Graepel J，et al. β-blocker/thiazide combination for treatment of hypertensive children：a randomized double-blind，placebocontrolled trial [J]. Pediatr Nephrol，2002，17（5）：345-350.
[18] The AGREE Ⅱ Instrument. Available：http://www.agreetrust.org Accessed 2014.1.12.
[19] 杨敬致，贾俊海，刘爱萍，等.儿童急性胃肠炎临床实践指南方法学质量评价[J].中国医药导刊，2018，20（2）：69-72.
[20] 张伶俐，李幼平，张川，等.中国儿童临床指南现状分析及循证临床指南评价[J].中国循证医学杂志，2011，11（9）：991-999.
[21] 韦当，王小琴，吴琼芳，等.2011年中国临床实践指南质量评价[J].中国循证医学杂志，2013，13（6）：760-763.
2020, Vol. 17 
京公网安备 11010502046598号