Effect of combination of Qiangli Loquat Dew and Western medicine on acute exacerbation of chronic bronchitis and its effect on inflammatory factors and quality of life
FAN Hongtao HUANG Xiaoping HUANG Xincheng HUANG Wencheng YAN Meihao HONG Yuancheng
Department of Respiratory Medicine, the 910th Hospital of Joint Logistic Support Force of the Chinese People′s Liberation Army, Fujian Province, Quanzhou 362000, China
Abstract：Objective To investigate the effect of combination of Qiangli Loquat Dew with Western medicine on acute exacerbation of chronic bronchitis and its effect on inflammatory factors and quality of life. Methods From February 2017 to February 2019, 98 cases with acute exacerbation of chronic bronchitis received by the 910th Hospital of Joint Logistic Support Force of the Chinese People′s Liberation Army were selected. The patients were randomly divided into the study group and the control group by random numbers method, with 49 cases in each group. The study group was treated with Qiangli Loquat Dew combined with western medicine, while the control group was treated with western medicine. Clinical efficacy, recovery time of clinical symptoms, inflammatory factors, quality of life and adverse reactions of patients were compared between the two groups. Results The total effective rate of the study group after 2 weeks of treatment was higher than that of the control group, and the difference was statistically significant (P ＜ 0.05). The remission time of cough, sputum, fever and lung ralogue symptoms in the study group was shorter than those in the control group, and the differences were statistically significant (all P ＜ 0.05). The serum levels of interleukin-6 (IL-6), IL-8 and tumor necrosis factor-α (TNF-α) of patients in the two groups decreased after 2 weeks of treatment compared with those before treatment, and the study group were lower than those in the control group, the differences were statistically significant (all P ＜ 0.05). The scores of physiological function, physical pain, role physical, general health, social function, energy, emotional function and mental status of patients in the two groups after 2 weeks of treatment were all higher than those before treatment, and the scores of the study group were higher than those in the control group, the differences were statistically significant (all P ＜ 0.05). There was no significant difference of the incidence of adverse reactions of patients between the two groups (P ＞ 0.05). Conclusion In the treatment of acute exacerbation of chronic bronchitis with combination of Qiangli Loquat Dew and Western medicine, the curative effect is definite, the level of inflammatory factors can be effectively improved, and the quality of life of patients can be improved without increasing the incidence of adverse reactions.
范洪涛 黄小平 黄鑫成 黄文铖 颜美好 洪原城. 强力枇杷露联合西药治疗慢性支气管炎急性加重期的效果及对炎性因子、生活质量的影响[J]. 中国医药导报, 2020, 17(4): 102-105.
FAN Hongtao HUANG Xiaoping HUANG Xincheng HUANG Wencheng YAN Meihao HONG Yuancheng. Effect of combination of Qiangli Loquat Dew and Western medicine on acute exacerbation of chronic bronchitis and its effect on inflammatory factors and quality of life. 中国医药导报, 2020, 17(4): 102-105.
2020, Vol. 17 
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