Effect of transrectal ultrasound conductance-guided administration drug in treating chronic bacterial prostatitis
YAO Aibing1 JIANG Qi1 MENG Xuhui2 JIN Yuming3 WEI Zhongqing2▲
1.Department of Urology Surgery, Nanjing Pukou Hospital, Jiangsu Province, Nanjing 210031, China;
2.Department of Urology Surgery, Nanjing Medical University Second Affiliated Hospital, Jiangsu Province, Nanjing 210000, China;
3.Department of Urology Surgery, NO.422 Hospital of PLA, Guangdong Province, Zhanjiang 524005, China
Abstract:Objective To compare the effect of transrectal ultrasound conductance-guided administration drug with oral medication in treating chronic bacterial prostatitis. Methods 80 patients with chronic bacterial prostatitis in the outpatient and hospitalization of the Nanjing Pukou Hosptial from January 2016 to January 2017 were selected and divided into two groups by envelope method. There were transrectal ultrasound conductance-guided administration drug group (group A) and oral administration group (group B), with 40 cases in each group. Both groups were treated with 21 days. The number of prostatic fluid leukocytes (WBC), the total integral of chronic prostatitis symptom (NIH-CPSI) and the total efficiency follow-up 1 month after treatment in the two groups were compared. Results The total efficiency, the number of prostatic fluid WBC and the total integral of NIH-CPSI in the group A were better than those in the group B, with statistically significant difference (P < 0.05). Conclusion Compared with oral medicine, the effect of transrectal ultrasound conductance-guided administration drug in treating chronic bacterial prostatitis is better.
[1] 米华,陈凯,莫曾南.中国慢性前列腺炎的流行病学特征[J].中华男科学杂志,2012,18(7):579-582.
[2] 商学军,黄宇烽,等.龙金通淋胶囊治疗慢性前列腺炎/慢性骨盆疼痛综合症的初步研究[J].中华男科学杂志,2006,12(4):371-374.
[3] 那彦群.中国泌尿外科疾病诊断治疗指南[M].北京:人民卫生出版社,2013.
[4] 周利平,陈娟英,沈华,等.前列康片联合头孢呋辛酯片对慢性前列腺炎患者血清细胞因子的影响及疗效分析[J].中国现代医生,2017,55(14):28-31.
[5] 姚德鸿.前列腺炎、前列腺增生症与前列腺癌[M].上海:上海科学普及出版社,2003.
[6] 李宏军,丘勇超,许蓬,等.征服前列腺炎[M].北京:中国医药科技出版社,2003.
[7] 郭应禄,李宏军.前列腺炎[M].2版.北京:人民军医出版社,2007.
[8] 李海松,韩亮,王彬.慢性前列腺炎的中医药研究进展与思考[J].环球中医药,2012,5(7):481-484.
[9] 杨武斌.针灸为主的临床治疗方案在慢性前列腺炎患者中的效果[J].中国医药科学,2017,7(1):70-73.
[10] Nickel JC,Roehrborn CG,O′Leary MP,et al. Examination of the relationship between symptoms of prostatitis and histological inflammation:baseline data from the REDUCE chemoprevention trial [J]. J Urol,2007,178(1):896-901.
[11] 赵丽杰,赵军凤,公艳玲,等.体外冲击波与高频热疗对慢性非细菌性前列腺炎的疗效比较[J].中国医学装备,2016,13(3):98-101.
[12] 李春弟,崔崑,蒋聿瑛,等.慢性前列腺炎/慢性骨盆疼痛综合征的发病相关危险因素分析[J].中国现代医生,2015,53(13):77-80.
[13] 赵耀东,韩豆瑛.温通针法靶向透刺治疗慢性前列腺炎临床观察[J].中国针灸,2013,33(10):897-899.
[14] 王建新,高佃军,杨波,等.心理干预疗法在治疗慢性前列腺炎中的应用[J].现代泌尿外科杂志,2010,15(4):297-299.
[15] ShafikA.Anal submucosal injection:a new route for drug administration. Ⅵ. Chronic prostatitics:a new modality of treatment with report of 11 cases [J]. Urology,1991,37(1):61-64.
[16] 潘小清,何燕芳,王坚,等.腔道介入配合中药灌肠治疗Ⅲ型慢性前列腺炎的临床研究[J].中国现代医学杂志,2011,21(27):3451-3455.
[17] Tang H,Wang CC,Blankschtein D,et al. An investigation of the role of cavitation in low-frequency ultrasound-mediated transdermal drug transport [J]. Pharm Res,2002, 19(8):1160-1169.
[18] 农礼铭. 240例慢性前列腺炎的腔道介入治疗疗效分析[J].中国医学创新杂志,2011,8(31):132-133.
[19] 晁华,马昆宏,刘娜,等.腔道介入治疗慢性前列腺炎1826例效果观察[J].中国性科学杂志,2012,21(4):20-22.
[20] 李海松,王彬,韩亮,等.脐疗联合栓剂治疗Ⅲ型前列腺炎(气滞血瘀型)80例临床研究[J].北京中医药大学学报:中医临床版,2013,20(2):21-23.