Research progress in immune cell therapy for hepatocellular carcinoma
HE Yulin1 MENG Zhongji1,2,3
1.Institute of Biomedical Research, Taihe Hospital of Shiyan City (Affiliated Taihe Hospital of Hubei University of Medicine), Hubei Province, Shiyan 442000, China; 2.Department of Infectious Disease, Taihe Hospital of Shiyan City (Affiliated Taihe Hospital of Hubei University of Medicine), Hubei Province, Shiyan 442000, China; 3.Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei Province, Shiyan 442000, China
Abstract:Hepatocellular carcinoma is one of the most common malignant tumors in the world, especially in China with the highest morbidity. Currently, hepatocellular carcinoma is mainly treated by surgery, radiotherapy, local ablation, hepatic artery chemoembolization, molecular targeted therapy, etc. Because of the occult onset of hepatocellular carcinoma, most patients have lost the opportunity for surgery when they are discovered, and the therapeutic effect is very limited. Therefore, it is of great significance to explore new treatment options. Tumor immune cell therapy is currently the most concerned emerging treatment, especially gene modified T cell therapy has shown great potential in the treatment of hepatocellular carcinoma. This paper will review the recent advances in immunotherapy for hepatocellular carcinoma.
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