Clinical effect of herbal fumigation and washing therapy of Zhuang medicine on chronic abacterial prostatitis
ZHU Min1 LU Zhihua2 DAI Fang1 HUANG Cunchao1 JIANG Jianling2 MAI Pengyu2 LIU Ying1
1.Department of Andrology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Guangxi Zhuang Autonomous Region, Nanning 530011, China; 2.Graduate School, Guangxi University of Chinese Medicine, Guangxi Zhuang Autonomous Region, Nanning 530001, China
Abstract:Objective To observe the clinical effect of herbal fumigation and washing therapy of Zhuang medicine on chronic abacterial prostatitis (CAP). Methods 160 CAP patients from January 2015 to August 2016 in Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine were randomly divided into treatment group and control group with 80 cases in each group by using random number table method. Treatment group was fumigated and washed with Qianlieshu external lotion, while control group was intervened with Qianlie′an Suppository. Both groups were treated with 28 days as a course of treatment. After one course of treatment, clinical total effective rate was compared between two groups. NIH-CPSI score, TCM syndrome score and levels of interleukin (IL)-2, IL-8 and IL-10 in prostatic fluid were compared between two groups before and after treatment. Results After treatment, total effective rate of treatment group was higher than that of control group (P < 0.05). After treatment, the scores of NIH-CPSI and TCM syndromes in two groups were lower than those before treatment (P < 0.05), and the scores in treatment group were lower than those in control group (P < 0.05). After treatment, the level of IL-8 in prostatic fluid of two groups was lower than that before treatment (P < 0.05), and the level of IL-8 in treatment group was lower than that in control group (P < 0.05). After treatment, the levels of IL-2 and IL-10 in prostatic fluid of both groups were higher than before treatment (P < 0.05), and treatment group was higher than control group (P < 0.05). Conclusion The fumigation and washing therapy of Zhuang medicine has better effect on CAP. This method can reduce the level of IL-8 in prostatic fluid and increase the levels of IL-2 and IL-10 in prostatic fluid. This may be one of the mechanisms of herbal fumigation and washing therapy for CAP in Zhuang medicine.
朱闽1 陆智华2 戴芳1 黄存超1 蒋建玲2 买鹏宇2 刘英1. 壮医药物熏洗疗法治疗慢性非细菌性前列腺炎的临床效果[J]. 中国医药导报, 2019, 16(24): 77-80.
ZHU Min1 LU Zhihua2 DAI Fang1 HUANG Cunchao1 JIANG Jianling2 MAI Pengyu2 LIU Ying1. Clinical effect of herbal fumigation and washing therapy of Zhuang medicine on chronic abacterial prostatitis. 中国医药导报, 2019, 16(24): 77-80.