Pregnancy outcome of patients with high-grade squamous intraepithelial lesion after conization
MA Quanfu1 DAI Xuan1 ZOU Miao1 WANG Chaonan1 ZHAO Yun2 HU Junbo3 WU Xufeng1
1.Department of Gynecology and Oncology, Maternal and Child Health Hospital of Hubei Province, Hubei Province, Wuhan 430070, China;
2.Department of Obstetrics, Maternal and Child Health Hospital of Hubei Province, Hubei Province, Wuhan 430070, China;
3.Department of Pathology, Maternal and Child Health Hospital of Hubei Province, Hubei Province, Wuhan 430070, China
Abstract：Objective To discuss the effect of cervical conization on pregnancy outcome of patients with high-grade squamous intraepithelial lesion (HSIL). Methods One hundred and fourteen patients with HSIL treated by cervical conization in Hubei Meternal and Child Health Hospital were included from December 2003 to December 2017, and all the patients were primigravid and successful delivery. Among them, 74 cases received high frequency wave loop resection (LEEP) and 40 cases received cold knife conization (CKC). The pregnancy outcome, delivery mode were compared between the two groups, and the effect of the interval time from pregnancy to operation on pregnancy outcome was observed. Results There were no significant differences in gestational weeks, preterm birth rate, premature rupture of membranes rate, low birth weight infants rate, average neonatal weight, cesarean section rate, and distribution of cesarean section indications between the two groups (P > 0.05). Among 114 delivery cases, the cesarean section rate was 70.2%. The interval time from pregnancy to operation had no significant effect on pregnancy outcome (P > 0.05). Conclusion Different cervical conization methods and the interval time from conization to pregnancy had no significant effect on the postoperative pregnancy outcome, but these women have tendency to choose cesarean section after conization.
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2019, Vol. 16 
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