Correlation of anemia status and left ventricular diastolic function in patients with coronary heart disease
XU Shiying1 YE Fang2 PI Lin1 HU Jiangqiao1 FU Lijuan1 ZHANG Mingming1
1.Department of Cardiology, Chuiyangliu Hospital Affiliated to Tsinghua University, Beijing 100022, China;
2.Department of Hematology, Chuiyangliu Hospital Affiliated to Tsinghua University, Beijing 100022, China
Abstract：Objective To investigate the correlation of anemia status and left ventricular diastolic function in patients with coronary heart disease. Methods The clinical data of 282 patients with coronary heart disease admitted to Department of Cardiology of Chuiyangliu Hospital Affiliated to Tsinghua University from January 2017 to April 2018 was analyzed retrospectively. According to whether there were anemia, the patients were divided into two groups, total 186 cases of patients without anemia were set as group A, total 96 cases of patients with anemia were set as group B. The age, blood pressure, body mass index (BMI), total cholesterol (TC), glycosylated hemoglobin (HbA1c), A peak, E/A, left ventricular end diastolic diameter (LVEDD), left ventricular posterior wall thickness (LVPWT) and the proportion of complications of the two groups were compared, and the hemoglobin level and related clinical indicators were analyzed by multivariate linear regression analysis. Results The levels of BMI, TC, E/A and diastolic blood pressure of group B were lower than those of group A, the differences were statistically significant (P ＜ 0.05). The levels of age, HbAlc, peak A value, LVEDD and LVPWT of group B were significantly higher than those of group A, the differences were statistically significant (P ＜ 0.05). There was no significant difference in the incidence of primary hypertension between the two groups (P ＞ 0.05). The incidence of diabetes and diastolic heart failure of group B was significantly higher than those of group A (P ＜ 0.05). Multivariate linear regression analysis showed that hemoglobin level was negatively correlated with age (β = 0.337) and positively correlated with E/A (β = 0.442), the differences were statistically significant (P ＜ 0.05). Conclusion The anemia status of patients with coronary heart disease can affect the left ventricular diastolic function. Therefore, it is necessary to pay attention to the correction of anemia in the course of clinical treatment, so as to protect cardiac function.
徐世莹1 叶芳2▲ 皮林1 胡江乔1 富丽娟1 张明明1. 贫血状态与冠心病患者左心室舒张功能的相关性[J]. 中国医药导报, 2019, 16(22): 87-89,97.
XU Shiying1 YE Fang2 PI Lin1 HU Jiangqiao1 FU Lijuan1 ZHANG Mingming1. Correlation of anemia status and left ventricular diastolic function in patients with coronary heart disease. 中国医药导报, 2019, 16(22): 87-89,97.
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2019, Vol. 16 
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