Abstract：Breast cancer is one of the most common malignant tumors in women and the leading cause of death from cancer. Tumor cell DNA is continuously released into the blood during the development of tumor. These circulating tumor DNA (ctDNA) carry the information of tumor-related gene mutation, making it a potential cancer biomarker. As a kind of liquid biopsy, ctDNA detection is simple and easy, and can dynamically monitor tumor progression and treatment response with minimally invasive methods. It has been widely studied in the field of breast cancer, and has potential clinical application value in the aspects of disease efficacy monitoring, drug resistance identification, recurrence prediction and prognosis judgment.
郝帅 田武国 高博 何渝军 罗东林. 循环肿瘤DNA在乳腺癌治疗中的应用进展[J]. 中国医药导报, 2019, 16(21): 43-46.
HAO Shuai TIAN Wuguo GAO Bo HE Yujun LUO Donglin. Application Progress of circulating tumor DNA in the treatment of breast cancer. 中国医药导报, 2019, 16(21): 43-46.
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2019, Vol. 16 
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