Retrospective analysis of prognostic factors in elderly patients with stage Ⅰ-ⅢA non-small cell lungcancer after radical resection
MI Yuling1 HU Xingsheng1 WANG Ziping2 ZHU Yixiang1
1.National Cancer Center Cancer Hospital, Chinese Academy of Medical Sciences Peking Union Medical College, Beijing 100021, China;
2.Peking University Cancer Hospital, Beijing 100142, China
Abstract：Objective To identify prognostic factors associated with survival in elderly patients with non-small cell lung cancer (NSCLC) after radical resection. Methods From August 2003 to August 2011, in Cancer Hospital, Chinese Academy of Medical Sciences Peking Union Medical College, the clinical data of 82 elderly patients (≥65 years old) with pathologic stage Ⅰ-ⅢA underwent radical resection were retrospective analyzed. And the correlation between clinical characteristics and prognostic factors was evaluated by Cox proportional hazards regression analysis. Results The median of DFS was 38.28 months (95% CI: 15.583-60.967 months). 1, 2, 5-year DFS rates were 73.2%,57.3% and 35.4%, respectively. Cox regression analysis showed: pathological type, lymph node involvement and ACT status were identified as the independent factors influenced the prognosis (P ＜ 0.05). Conclusion Pathological type, lymph node involvement and ACT status are identified as the independent factors influencing the prognosis of NSCLC elderly patients.
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2017, Vol. 14 
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