Meta analysis of endoscopic third ventriculostomy and ventriculoperitoneal shunt for treating hydrocephalus in chirdren
FENG Xin1 HUANG Xintao2 HE Yong1 GUO Xiaolong2 ZHAO Xueming2
1.The First Clinical Medical College of Shanxi Medical University, Shanxi Province, Taiyuan 030000, China;
2.Department of Neurosurgery, the First Hospital of Shanxi Medical University, Shanxi Province, Taiyuan 030000, China
Abstract：Objective To investigate the clinical effects of the third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) in the treatment of hydrocephalus in children. Methods Relevant literatures collected from the establishment of the database to October 2018 were obtained according to inclusion and exclusion criteria through computer retrieval of China national knowledge network, Wanfang data knowledge service platform, VIP database, PubMed, Embase and Cochrane library databases. The Newcastle-Ottawa scale and Jadad scale were used for literature quality evaluation, and Stata 15.0 software was used for Meta analysis. Results There was no statistically significant difference in the effective rate (OR = 1.50, 95%CI: 0.82-2.74, P = 0.189), the incidence of total postoperative complications (OR = 0.73, 95%CI: 0.36-1.51, P = 0.394), the incidence of intracranial hematoma after operation (OR = 1.16, 95%CI: 0.51-2.66, P = 0.726) of ETV and VPS in the treatment of hydrocephalus in children. The incidence of postoperative intracranial infection (OR = 0.26, 95%CI: 0.12-0.57, P = 0.001), the incidence of postoperative shunt obstruction (OR = 0.17, 95%CI: 0.06-0.43, P = 0.000), the rate of reoperation after operation (OR = 0.20, 95%CI: 0.07-0.56, P = 0.002) were statistically significant. Conclusion ETV is superior to VPS in postoperative complications and whether or not to have another operation. More advantages still need to be further observed in clinical studies.
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2019, Vol. 16 
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