经颅磁刺激在癫痫临床应用的研究进展

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摘要癫痫是中枢神经系统常见疾病之一，严重危害人类健康。大约30%的癫痫患者通过现有抗痫药物的治疗仍然不能得到有效控制，因此神经调控方法，如迷走神经刺激、深部脑刺激和经颅磁刺激等成为人们关注的焦点。基于无创、无痛、有效、操作方便等多重优点，经颅磁刺激逐渐被应用于癫痫患者的诊断和治疗方面。本文就经颅磁刺激在癫痫疾病的诊断和治疗两方面的内容进行综述，总结其最新研究进展，并指出其存在的不足与缺陷，为今后癫痫的诊断和治疗制订优化和个性化的经颅磁刺激方案。

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	王林晓张青周先举

关键词 ：经颅磁刺激, 癫痫, 诊断, 治疗

Abstract：Epilepsy is one of the common diseases of the central nervous system, which seriously endangers human health. About 30% of patients with epilepsy can not be effectively controled through the treatment of existing anti-epileptic drugs, so neuromodulation methods such as vagus nerve stimulation, deep brain stimulation and transcranial magnetic stimulation have become the focus of attention. Based on the multiple advantages of non-invasive, painless, effective, and convenient operation, transcranial magnetic stimulation is gradually applied to the diagnosis and treatment of patients with epilepsy. This article reviews the content of transcranial magnetic stimulation in the diagnosis and treatment of epilepsy, summarizes its latest research progress, and points out its shortcomings and defects, and develops an optimized and personalized transcranial magnetic stimulation solution for the diagnosis and treatment of epilepsy in the future.

Key words： Transcranial magnetic stimulation Epilepsy Diagnosis Treatment

基金资助:国家自然科学基金资助项目（81471338、816712 84、81803498）；
江苏省常州市卫生计生委青年人才科技项目（QN201719）。

通讯作者: 周先举（1969.8-），男，博士，博士生导师，研究员；研究方向：神经疾病和康复治疗。

作者简介: 王林晓（1986.6-），女，博士；研究方向：神经药理学。

引用本文:

王林晓张青周先举. 经颅磁刺激在癫痫临床应用的研究进展[J]. 中国医药导报, 2019, 16(19): 47-50.
WANG Linxiao ZHANG Qing ZHOU Xianju. Research progress on clinical application of transcranial magnetic stimulation in epilepsy. 中国医药导报, 2019, 16(19): 47-50.

链接本文:

http://www.yiyaodaobao.com.cn/CN/ 或 http://www.yiyaodaobao.com.cn/CN/Y2019/V16/I19/47

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