Study on the relationship between traditional Chinese medicine syndrome type distribution and anxiety and depression in patients with gastroesophageal reflux disease
XU Duo LI Shu LI Shuang
Department of Gastroenterology, Baoshan Branch, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201900, China
Abstract：Objective To investigate the relationship between traditional Chinese medicine syndrome types of gastroesophageal reflux disease (GERD) and disease duration, age, gender and self-anxiety and depression. Methods From January 2010 to April 2012, 146 patients from the Department of Gastroenterology of Shanghai Longhua Hospital who met the GERD diagnosis of Western medicine were selected for questionnaire survey. Data were collected for statistical analysis to explore the relationship between syndrome types and related factors. Results Among the 146 cases included, 56 cases were spleen-deficiency type, 49 cases were liver-stomach-stagnation type, 36 cases were qi-stagnation-resistance type, 4 cases were biliary-heat-stomach type, and 1 case was phlegm-blocking type. GERD always occurred in 40-59 years old patients, and the incidence of each type of syndrome was basically the same in this age group. In 20-39 years old, most patients with GERD were liver-stomach-stagnation type, while those over 60 years old were mainly spleen-deficiency type. The course of disease in patients of spleen-deficiency type was significantly longer than that in patients of liver-stomach-stagnation type and qi-stagnation-resistance type (P = 0.02). Gender was correlated with GERD of liver-stomach-stagnation type and qi-stagnation-resistance type (P = 0.003, P = 0.001). Males were significantly more than females in GERD of liver-stomach-stagnation type, while females were significantly more than males in GERD of qi-stagnation-resistance type. The scores of anxiety and depression of the three syndromes were significantly different (P = 0.02, P < 0.001). Conclusion The occurrence of GERD is significantly correlated with age. Anxiety and depression are common in patients with liver-stomach-stagnation type and qi-stagnation-resistance type.
许多 李书 李爽. 胃食管反流病中医证型分布与焦虑抑郁关系的研究[J]. 中国医药导报, 2019, 16(17): 27-30.
XU Duo LI Shu LI Shuang . Study on the relationship between traditional Chinese medicine syndrome type distribution and anxiety and depression in patients with gastroesophageal reflux disease. 中国医药导报, 2019, 16(17): 27-30.
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2019, Vol. 16 
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