Relationship between Q-T interval dispersion on electrocardiogram and adverse cardiac events in patients with type 2 diabetes mellitus and chronic heart failure
LIU Juan SU Bing LI Shuo WANG Wei SHEN Lin WANG Yajuan
Department of Clinical Electrophysiology, Harrison International Peace Hospital, Hebei Province, Hengshui 053000, China
Abstract:Objective To study the relationship between Q-T interval dispersion (QTd) on electrocardiogram and adverse cardiac events in patients with type 2 diabetes mellitus and chronic heart failure. Methods Two hundred patients with type 2 diabetes mellitus and chronic heart failure admitted to Hengshui Harrison International Peace Hospital in Hebei Province from February 2016 to December 2017 were selected as the subjects. All patients were followed up for 6 months, and they were divided into adverse cardiac events group (n = 63) and non-adverse cardiac events group (n = 137) according to whether the patient had adverse cardiac events. The basic data, the level of biochemical index and echocardiographic index of the two groups were compared, and multivariate Logistic regression analysis was performed. Results The level of uric acid (UA), QTd and corrected QTd (QTcd) in the adverse cardiac events group was higher than that in the non-adverse cardiac events group (P < 0.05). The left ventricular ejection fraction (LVEF) level in the adverse cardiac events group was lower than that in the non-adverse cardiac events group (P < 0.05). The multiple Logistic regression analysis showed that UA, QTd and QTcd were independent risk factors for the occurrence of adverse cardiac events in patients with type 2 diabetes mellitus and chronic heart failure (P < 0.05), while LVEF was a protective factor (P < 0.05). Conclusion The increase of QTd and QTcd in electrocardiogram in patients with type 2 diabetes mellitus and chronic heart failure increases the risk of adverse cardiac events, which is worthy of clinical attention.
刘娟 苏兵 李硕 王薇 沈林 王亚娟. 2型糖尿病伴慢性心力衰竭患者心电图Q-T间期离散度与心脏不良事件的关系研究[J]. 中国医药导报, 2019, 16(14): 56-59.
LIU Juan SU Bing LI Shuo WANG Wei SHEN Lin WANG Yajuan. Relationship between Q-T interval dispersion on electrocardiogram and adverse cardiac events in patients with type 2 diabetes mellitus and chronic heart failure. 中国医药导报, 2019, 16(14): 56-59.