人参皂苷Rh2的药理活性研究进展
徐文 曹辉 杨远荣
湖北省荆州市中心医院药学部,湖北荆州 434020
Advances in pharmacological effects of ginsenoside Rh2
XU Wen CAO Hui YANG Yuanrong
Department of Pharmacy, Jingzhou Central Hospital, Hubei Province, Jingzhou 434020, China
摘要 人参皂苷Rh2是从红参中提取得到的一种二醇型低糖链皂苷单体,也是人参中主要活性成分之一。人参皂苷Rh2因其代谢作用多样性,药学工作者在深入研究过程中发现其具有多种药理活性,尤其在抗肿瘤活性方面表现显著,取得了一定的进展。作者通过查阅国内外近年来大量文献,从抗肿瘤、改善心肌缺血、抗子宫内膜异位症、抗过敏、调节免疫功能、防辐射、抗哮喘及抗抑郁等方面对人参皂苷Rh2的药理活性与作用机制进行分析和归纳,并进行综述,以期为药学工作者更深入的研究和开发利用人参皂苷Rh2提供参考。
关键词 :
人参皂苷Rh2 ,
皂苷单体 ,
药理活性 ,
作用机制
Abstract :Ginsenoside Rh2 has be extracted from red ginseng as a diol-based low-sugar saponin monomer and one of the main active ingredients in ginseng. Ginsenoside Rh2 is discovered that it has a variety of pharmacological activity by pharmacy workers in the depth of the study , and was made some progress especially in anti-tumor activity. the pharmacological effects of ginsenoside Rh2 are analyzed and summarized by The authors from a lot of literature at home and abroad on the aspects of anti-tumor, improving myocardial ischemia, anti-endometriosis, anti-allergy, immune function, radiation protection, anti-asthma and antidepressant activity and mechanism of action, this review studies and develops the use of ginsenoside Rh2 in order to provide reference.
Key words :
Ginsenoside Rh2
Saponin monomer
Pharmacological effects
Mechanism
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