Abstract:Objective To establish the quality standard of Gouju Capsules. Methods The main ingredients of Ramudus Uncaria Cum Uncis, Epimedium were identified by TLC. Content of icariin was determined by UV-HPLC. The content of the berberine was determined by HPLC; the column of Agilent ZORBAX SB-C18(150 mm×4.6 mm, 5 μm) was used. The mobile phase was ocetonitrile-water (25∶75), the column temperature of 30℃, at the flow of 1.0 mL/min and detection wavelength was 270 nm. Results The spots on TLC plates were distinct, without interference. A good linearity of icariin was in the ranges of 15-150 μg/mL (r=0.9996). The average recovery was 100.9% (RSD =2.77%). Conclusion The results of this experiment are accurate, simple and easy to control. It can be used as a quality standard for Gouju Capsules.
朱和平 韩晓珂 王权 祁俊. 钩菊胶囊质量标准研究[J]. 中国医药导报, 2017, 14(28): 31-33,37.
ZHU Heping HAN Xiaoke WANG Quan QI Jun. Research on quality standard of Gouju Capsules. 中国医药导报, 2017, 14(28): 31-33,37.