Clinical effect of Liangxue Pingyin Decoction assisted by Jinhuang Ointment moving cupping in the treatment of psoriasis
ZHANG Shuai1 YANG Zhibo2 TANG Xueyong2 LUO Hong1 LI Liqin1
1.Department of Dermatology & STD, the First Hospital of Changsha, Hu′nan Province, Changsha 410005, China;
2.Department of Dermatology & STD, the Second Affiliated Hospital of Hu′nan University of Chinese Medicine, Hu′nan Province, Changsha 410005, China
Abstract：Objective To explore the clinical effect of Liangxue Pingyin Decoction assisted by Jinhuang Ointment moving cupping in the treatment of psoriasis. Methods A total of 110 patients with psoriasis vulgaris admitted to the First Hospital of Changsha from February 2016 to January 2018 were selected. According to the random number table method, they were divided into combined group and control group, with 55 cases in each group. Both groups were treated with Western medicine basic therapy and Liangxue Pingyin Decoction, and the combined group was also treated with Jinhuang Ointment moving cupping as an auxiliary treatment, the course was 2 months. The inflammatory index, immunological index, psoriasis area disease severity (PASI) score and dermatology life quality index (DLQI) before and after treatment were compared between the two groups. Results There were no significant differences of interleukin-17 (IL-17), interleukin-23 (IL-23), immune globulin G (IgG), immune globulin A (IgA), immune globulin M (IgM), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) levels, and the scores of PASI, DLQI between the two groups before treatment (P ＞ 0.05). After treatment, the levels of IgG, CRP, ESR, IL-17, IL-23 and the scores of PASI and DLQI of the two groups were significantly lower than those before treatment (P ＜ 0.05), the levels of IgM were significantly higher than those before treatment (P ＜ 0.05). After treatment, the levels of IL-17, IL-23, IgG, CRP, ESR and the scores of PASI and DLQI of the combined group were lower than those of the control group (P ＜ 0.05), the level of IgM in the combined group was higher than that in the control group (P ＜ 0.05). Conclusion Traditional Chinese medicine prescription Liangxue Pingyin Decoction assisted by Jinhuang Ointment moving cupping in the treatment of psoriasis can effectively improve the patients′ conditions, reduce the serum levels of IL-17, IL-23, CRP, ESR, regulate the immune function of patients, raise the quality of life of patients.
2019, Vol. 16 
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