Influencing factors of successful extubation and withdrawal in patients with primary cerebral hemorrhage and respiratory failure
LIU Jun1 HUANG Yan1 WU Rong1 HUANG Fang1 LI Xiangmin2
1.Department of Emergency, Changsha Fourth Hospital, Hu′nan Province, Changsha 410001, China;
2.Department of Emergency, Xiangya Hospital, Central South University, Hu′nan Province, Changsha 410000, China
Abstract：Objective To investigate the influencing factors of successful extubation and withdrawal in patients with primary cerebral hemorrhage and respiratory failure. Methods From January 2017 to June 2018, 82 patients with primary cerebral hemorrhage complicated with respiratory failure were selected from the Changsha Fourth Hospital ("our hospital" for short). They were all treated with invasive mechanical ventilation in our hospital. They were divided into success group (n = 63) and failure group (n = 19) according to whether the extubation and withdrawl was sucessful. The clinical data of the two groups were compared. Logistic regression was used to analyze the influencing factors of successful extubation and withdrawal in patients with primary cerebral hemorrhage and respiratory failure. Results The successful rate of extubation and withdrawal was 76.83% and the failure rate was 23.17%. The age, bleeding volume, history of chronic obstructive pulmonary disease (COPD) and National Institute of Health Stroke scale (NIHSS) score of the failure group were significantly higher than those of the success group (P < 0.05), while Glasgow Coma Scale score (GCS score) and serum albumin at extubation were significantly lower than those of the success group (P < 0.05); age, bleeding volume, history of COPD, and serum albumin at the time of extubation were the influencing factors for successful extubation and withdrawal in patients with primary cerebral hemorrhage complicated with respiratory failure (OR = 2.197, 1.578, 2.275, 0.582, P < 0.05). Conclusion The influencing factors of successful extubation and withdrawal in patients with primary cerebral hemorrhage and respiratory failure include age, amount of bleeding, COPD history and serum albumin level during extubation. The relevant influencing factors should be considered in the course of treatment and timely intervention.
2019, Vol. 16 
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