Meta-analysis on comparison of clinical effect of harmonic scalpel and electro-cautery in mixed hemorrhoid surgery
XIONG Caiwen1 ZENG Xiangyun1▲ LUO Zhanbin2 GU Haimei1
1.The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510405, China;
2.Department of Anorectum, Traditional Chinese Medical Hospital of Guangdong Province, Guangdong Province, Guangzhou 510120, China
Abstract:Objective To compare and analyze the clinical effect of harmonic scalpel and electro-cautery in the treatment of mixed hemorrhoids. Methods Domestic and foreign randomized controlled trial literatures on the treatment of mixed hemorrhoids with harmonic scalpel and electro-cautery were collected by searching domestic and foreign databases (PubMed, Medline, Embase, CNKI, Vip, Wanfang, etc), websites (The british library, etc), grey literatures and retrospecting literatures, which were published from January 2001 to December 2008. According to the article evaluation quality and screening methods, qualified articles were filtered, relevant clinical effect indexes were extracted. RevMan 5.2 software was used for Meta-analysis. Results A total of 8 randomized controlled trials (854 patients with mixed hemorrhoids) were included, the Meta-analysis showed that the average operation time, hospitalization time, postoperative pain time in the harmonic scalpel group were shorter than those in the electro-cautery group, the amount of bleeding in the operation, pain scores at day 1 and 3 after surgery were lower than those in the electro-cautery group, the incidence of short-term postoperative complications (urinary retention, anal edema, postoperative secondary bleeding, anal distenation) and postoperative anal stenosis were lower than those in the electro-cautery group, the differences were statistically significant (P < 0.05 or P < 0.01). However, there was no statistically significant difference in the incidence of anus incontinence between the two groups (P > 0.05). Conclusion Compared with electro-cautery, harmonic scalpel has the advantages of short operation time, less intraoperative blood loss, low incidence of postoperative complications and short hospitalization time in the treatment of mixed hemorrhoids, it is safer and more effective, and is worthy of clinical application.