Analysis of related factors of lower extremity deep venous thrombosis in pregnant women
ZHANG Chunmei1 YANG Tao2 AN′na1 SUN Lijun1 WU Jun1
1.Department of Gynaceology and Obstetrics, Maternal and Child Health Hospital Tangshan, Heibei Province, Tangshan 063000, China;
2.Department of Vascular Surgery, Tangshan Gongren Hospital, Heibei Province, Tangshan 063000, China
Abstract:Objective To explore the related factors and diagnosis and treatment scheme of lower extremity deep venous thrombosis in pregnant women. Methods From June to December 2016, pregnant women in Department of Obstetrics of Tangshan City Maternity and Child Care Hospital and Department of Vascular Surgery of Tangshan Gongren Hospital in Heibei Province were selected as research subjects, 73 pregnant women with deep venous thrombosis of lower extremities were enrolled in study group, and 73 pregnant women with non deep venous thrombosis were selected as control group. The incidence of deep venous thrombosis, constituent ratio of risk factors, diagnosis and treatment plan, and the prognosis of treatment were discussed. Results There were 73 cases of deep venous thrombosis occurred in 6425 pregnant women, and the incidence rate was 1.14%. Multivariate Logistic regression analysis showed that age, body mass index, puerperal bed rest time, cesarean section, postpartum hemorrhage, gestational hypertension and gestational diabetes were risk factors for the occurrence of deep vein thrombosis in maternal lower limbs (P < 0.05). The symptoms such as swelling of the lower extremities were relieved, and 8 of them developed deep vein thrombosis syndrome. After thrombolytic therapy, the thigh diameter, leg circumference and venous patency score were significantly improved in 62 patients, compared with before thrombolytic therapy (P < 0.01). During the follow-up, patients with deep venous thrombosis of the lower extremities were dissolved, 46 cases of venous lumen recovered unobstructed and 5 cases had mild filling defect, of which 5 cases had deep venous thrombosis syndrome. Conclusion The pregnant women are high risk group of deep venous thrombosis of lower extremity. The intervention on the risk factors of deep venous thrombosis of the lower limbs of pregnant and parturient is beneficial to reduce the occurrence of deep vein thrombosis of lower extremity. The reasonable treatment plan can improve the effect of treatment and ensure the safety of mother and child.