Preventive effect of Low Molecular Weight Heparin on preoperative deep vein thrombosis in elderly patients with intertrochanteric fracture
ZHANG Jianli1 YAN Hua2 YANG Hui1
1.Department of Orthopedics, Jizhong Energy Fengfeng Group General Hospital, Hebei Province, Handan 056200, China;
2.Department of Pharmacy, Jizhong Energy Fengfeng Group General Hospital, Hebei Province, Handan 056200, China
Abstract:Objective To investigate the preventive effect of Low Molecular Weight Heparin on preoperative deep vein thrombosis in elderly patients with intertrochanteric fracture. Methods Fifty-two elderly patients with intertrochanterteric fracture in accordance with the inclusion criteria admitted to Jizhong Energy Fengfeng Group General Hospital from August 2015 to July 2018 were selected as the experimental group, they were given Low Molecular Weight Heparin to prevent preoperative deep venous thrombosis after admission. 45 elderly patients with intertrochanterteric fracture without using Low Molecular Weight Heparin to prevent preoperative deep venous thrombosis from December 2012 to July 2014 were selected as the control group. The incidence of preoperative deep venous thrombosis in the two groups was calculated. SPSS 21.0 sofyware was used to analyze the incidence of preoperative deep venous thrombosis and the type distribution of deep venous thrombosis between the two groups. Results The incidence of preoperative deep venous thrombosis had no significant difference between the experimental group [13.5% (7/52)] and the control group [24.4% (11/45)] (P = 0.165). There was no significant difference in the type distribution of deep vein thrombosis between the two groups (P = 1.000). Conclusion The effect of using only Low Molecular Weight Heparin in prevention of deep vein thrombosis in elderly patients with intertrochanteric fracture may not be obvious. Other physical methods still need to be combined for prevention.