Anesthetic effect of Dexmetomidine combined with Sevoflurane inhalation in hysteroscopic electric resection
HUANG Qun1,2 LIU Jing1 MAO Shanshan1 QI Dunyi2 Qin Wenmin3
1.Department of Anesthesiology, Xuzhou City Hospital of TCM, Jiangsu Province, Xuzhou 221000, China;
2.School of Anesthesiology, Xuzhou Medical University, Jiangsu Province, Xuzhou 221000, China;
3.Department of Gynaecology, Xuzhou City Hospital of TCM, Jiangsu Province, Xuzhou 221000, China
Abstract:Objective To investigate the anesthetic effect of Dexmetomidine combined with Sevoflurane inhalation in hysteroscopic electric resection. Methods From April 2016 to April 2018, 98 patients received hysteroscopic electric resection treatment in Xuzhou City Hospital of TCM were taken as the study subjects, and they were divided into observation group and control group according to the random number table method, with 49 cases in each group. Patients in the control group were given Sevoflurane inhalation anesthesia intervention, while patients in the observation group were given Dexmetomidine intravenous injection on the basis of the control group. The levels of the hemodynamic indexes before the start of anesthesia (T0), intraoperative (T1), postoperative wakefulness (T2), 10 min after wakefulness (T3) of two groups were compared. The sedation scores (Ramsay), alert/calm observed score (OAA/S), harem shrinkage pain, and intraoperative adverse reactions of two groups were observed after operation. Results The heart rate of the observation group was lower than the control group at T1, T2 and T3, and the differences were statistically significant (all P < 0.05). The scores of Ramsay and OAA/S in the observation group were higher than those in the control group, and the differences were statistically significant (all P < 0.01). The excellent and good rate of postoperative hysterectomy in the observation group was higher than that in the control group, and the difference was statistically significant (P < 0.05). The incidence of respiratory inhibition in the observation group was lower than the control group, the difference was statistically significant (P < 0.05). Conclusion Dexmetomidine intravenous injection combined with Sevoflurane inhalation anesthesia in hysteroscopic electric resection has significant effect of anesthesia, advantageous to maintain patients′ hemodynamic stability, reduce the risk of adverse reactions, and with good security, which is worthy of clinical popularization and application.