氪黄激光治疗黄斑外息肉状脉络膜血管病变的效果

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摘要目的观察氪黄激光治疗黄斑外息肉状脉络膜血管病变（PCV）的效果。方法选取邯郸市眼科医院2015年6月～2017年6月根据临床特征和病史并经过眼底荧光血管造影（FFA）+吲哚菁绿血管造影（ICG）及光相干断层扫描（OCT）确诊病灶距离黄斑中心区500 μm以外的PCV患者11例（11只眼），采用氪黄激光治疗2～3次，每次激光治疗间隔15 d~1个月，行再次激光治疗是根据眼底彩照病灶的颜色、激光光斑色素的反应、眼底造影（FFA+ICGA）、OCT检查病灶有无渗漏来决定，随访并观察6～12个月，每次观察患者的视力及最佳矫正视力、眼底血管造影（FFA+ICGA）、光线干断层扫描（OCT）检查结果。结果 3只眼进行2次激光治疗，8只眼进行3次激光治疗。6例（6只眼）患者主诉视物较治疗前清楚，视物变形基本消失；2例（2只眼）患者主诉视物较治疗前稍好转，眼前黑影减小；3例（3只眼）患者主诉视力提高明显，黑影消失。最佳矫正视力0.1～0.6。FFA+ICG检查PCV病灶均萎缩。结论氪黄激光治疗黄斑中心凹500 μm以外的PCV疗效确切，能有效稳定和提高患者的视力，阻止病变进一步进展，经济有效。

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	申然1 王凤华2▲ 郭黎霞1 杨丽萍1 王艳娜1

关键词 ：息肉状脉络膜血管病变, 氪黄激光, 眼底荧光血管造影, 光学相干断层扫描

Abstract：Objective To observe the effect of krypton yellow laser for polypoidal choroidal vasculopathy (PCV) outside the macular. Methods Eleven cases (11 eyes) with PCV located out of the macular central fovea with 500 μm were selected in Handan City Eye Hospital from June 2015 to June 2017, that were diagnosed by clinical features, medical history, fundus fluorescence angiography (FFA), indocyanine green angiography (ICGA) and optical coherence tomography (OCT). All patients were treated with krypton yellow laser 2-3 times with interval of 15 days to 1 month. The re-treatment indications were according to the color fundus lesions, the reaction of laser, fundus angiography (FFA and ICGA) and OCT examination. All the patients were followed up for 6 to 12 months. Visual acuity, the best corrected visual acuity, FFA, ICGA and OCT results were observed. Results There were 3 eyes that were treated with laser 2 times, while 8 eyes were treated with 3 times. There were 6 patients (6 eyes) replied that the visual acuity improved compared with that before treatment and visual deformation mainly eliminated. There were 2 patients (2 eyes) that had a slightly improvement in the visual acuity and the shadow decreased. Three patients (3 eyes) had significant visual improvement with shadow disappearing. The best corrected vision acuity was 0.1-0.6. FFA and ICG results showed atrophy of PCV lesions. Conclusion Effect of krypton yellow laser treatment for PCV located out of the macular central fovea with 500 μm was reliable, that can stabilize and improve patients′ vision acuity effectively, preventing the further progress of PCV, inexpensive and effective.

Key words： Polypoidal choroidal vasculopathy Krypton yellow laser Fundus fluorescein angiography Optic coherence tomography

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引用本文:

申然1 王凤华2▲ 郭黎霞1 杨丽萍1 王艳娜1. 氪黄激光治疗黄斑外息肉状脉络膜血管病变的效果[J]. 中国医药导报, 2018, 15(30): 98-101.
SHEN Ran1 WANG Fenghua2▲ GUO Lixia1 YANG Liping1 WANG Yanna1. Efficacy of krypton yellow laser for polypoidal choroidal vasculopathy outside the macular. 中国医药导报, 2018, 15(30): 98-101.

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http://www.yiyaodaobao.com.cn/CN/ 或 http://www.yiyaodaobao.com.cn/CN/Y2018/V15/I30/98

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