半月节低温等离子消融术治疗原发性三叉神经痛第三支病变的临床效果

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摘要目的探讨CT引导下三叉神经半月节低温等离子消融术治疗原发性三叉神经痛仅第三支病变的临床效果和并发症。方法选取2017年1月~2018年3月于首都医科大学宣武医院原发性三叉神经痛仅第三支病变接受微创手术治疗的患者60例，采用随机数字表法将其分为C组和R组，每组各30例。C组术中给予低温等离子消融，R组术中给予射频热凝。记录分析两组患者术前（T0）及术后即刻（T1）、1周（T2）、１个月（T3）、3个月（T4）的疼痛视觉模拟评分（VAS）、面部麻木评分、咀嚼肌力评分及患者满意度。结果两组患者术后疼痛均明显缓解，手术前后各时间点两组VAS评分比较，差异无统计学意义（P > 0.05）；T1、T2、T3、T4各时点，C组面部麻木评分和咀嚼肌力评分均明显低于R组，差异均有高度统计学意义（P < 0.01）；C组患者满意度显著高于R组，差异有高度统计学意义（P < 0.01）。结论 CT引导下三叉神经半月节低温等离子消融术治疗原发性三叉神经痛仅第三支病变的效果好且安全，值得临床进一步探讨推广。

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	贺海丽1
	2 杨立强1 何亮亮1 倪家骧1▲ 宋胜文3

关键词 ：低温等离子消融术, 原发性三叉神经痛, 第三支病变, 三叉神经半月节

Abstract：Objective To discuss the clinical effect and complication of trigeminal ganglion low temperature plasma ablation in the treatment of the third branches (V3) lesion of idiopathic trigeminal neuralgia. Methods Sixty patients with V3 of idiopathic trigeminal neuralgia treated in Department of Pain Management, Xuanwu Hospital, Capital Medical University from January 2017 to March 2018 were enrolled, and they were divided into Group C and Group R by random number table method, with 30 cases in each group. The Group C was given trigeminal ganglion low temperature plasma ablation, the Group R was given radiofrequency thermocoagulation. The VAS, facial numbness score, masticatory muscle strength score before surgery (T0) and immediately (T1), 1 week (T2), 1 month (T3), 3 months (T4) after surgery and patients′ satisfaction were recorded and analyzed. Results The pain of patients in the two groups was significantly relieved, and there was no statistically significant difference between the two groups before and after the surgery (P > 0.05). The scores of facial numbness and masticatory muscle strength at each time point after surgery in Group C were significantly lower than those in Group R, the differences were statistically significant (P < 0.01). The satisfaction of patients in Group C was significantly higher than that in Group R, the difference was statistically significant (P < 0.01). Conclusion CT guided trigeminal ganglion low temperature plasma ablation is a safe and effective treatment for idiopathic trigeminal neuralgia with only V3, it is worthy of further clinical exploration and extension.

Key words： Low temperature plasma ablation Idiopathic trigeminal neuralgia The third branches lesion Trigeminal ganglion

基金资助:北京市属医院科研培育计划项目（PX2018034）。

通讯作者: ▲通讯作者

引用本文:

贺海丽1,2 杨立强1 何亮亮1 倪家骧1▲ 宋胜文3. 半月节低温等离子消融术治疗原发性三叉神经痛第三支病变的临床效果[J]. 中国医药导报, 2018, 15(28): 107-110.
HE Haili1,2 YANG Liqiang1 HE Liangliang1 NI Jiaxiang1▲ SONG Shengwen3. Clinical effect of trigeminal ganglion low temperature plasma ablation in the treatment of the third branches lesion of idiopathic trigeminal neuralgia. 中国医药导报, 2018, 15(28): 107-110.

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http://www.yiyaodaobao.com.cn/CN/ 或 http://www.yiyaodaobao.com.cn/CN/Y2018/V15/I28/107

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