1.Department of Psychiatry, Brain Hospital of Hu′nan Province, Changsha 410007, China;
2.Department of Psychiatry, the Second Xiangya Hospital of Central South University, Hu′nan Province, Changsha 410000, China
Abstract:Objective To study the characteristics of neurocognitive impairment in alcohol-dependent patients with aggressive behavior. Methods 100 patients with alcohol dependence were enrolled in Brain Hospital of Hu′nan Province from January 2015 to January 2016. The patients were divided into two groups according to the explicit behavior attack scale. The 50 patients with aggressive behavior were considered as the observation group, 50 patients without aggressive behavior were considered as the control group. According to the Wechsler adult intelligence scale, Stroop test and Wisconsin card sorting test, the cognitive function impairment, memory function, attention and executive function of the two groups were compared. Results The mean score of Wechsler adult intelligence scale and memory quotient in the observation group were significantly lower than those of the control group, the differences were statistically significant (P < 0.05). The ST-CW test score and the ST-C test score in the observation group were significantly lower than those of the control group, the differences were statistically significant (P < 0.05). The working memory capacity score and the cognitive transfer ability score of the observation group were significantly lower than those of the control group, the differences were statistically significant (P < 0.05). Conclusion Alcohol-dependence can impair the cognitive function of the patients. The neurocognitive dysfunction of alcohol-dependence patients with aggressive behavior is more serious. Most patients show the reduction of memory function, attention and executive function. Cognitive impairment of consciousness is also an important factor that leads to aggressive behavior in patients.
[1] 周旭辉,刘学军,郭育君,等.伴攻击行为酒精依赖患者的认知功能特征性研究[C]//2015全国药物滥用防治研讨会暨第九届内地与港澳地区药物滥用防治研讨会论文集,2015:243-248.
[2] 张华.开放病房精神疾病患者攻击行为的原因分析[J].中国实用神经疾病杂志,2012,15(2):12-13.
[3] Gruenewald P,Ponicki W,Mitchell P. Suicide rates and alcohol consumption in the United States,1970-89 [J]. Addiction,2012,90(8):1063.
[4] 张丞,邹韶红,董红斌,等.有家庭暴力行为酒依赖患者社会支持与应对方式的研究[J].四川精神卫生,2014,32(5):443-445.
[5] 陈红英,史诗洁,朱新,等.精神分裂症认知功能评测量表与韦氏成人智力量表及韦氏记忆量表的相关性研究[J].神经疾病与精神卫生,2013,13(1):40-43.
[6] 谭云龙,邹义壮,屈英,等.威斯康星卡片分类测验常用指标的稳定性分析[J].中国心理卫生杂志,2002,16(12):831-833.
[7] 舒畅,肖玲,王熇生,等.首发精神分裂症患者威斯康星卡片分类测验中的脑功能障碍研究[J].神经损伤与功能重建,2014,9(3):233-235.
[8] Skog OJ. Alcohol and suicide in Denmark 1911-24--experiences from a 'natural experiment'[J]. Addiction,1993, 88(9):1189.
[9] 邹韶红,赵宗峰,马瑞,等.酒精依赖患者家庭暴力行为与单胺氧化酶A关联分析[J].中华内科杂志,2013, 52(8):682-683.
[10] 黄理钧,谢楠,龚俊华,等.伴和不伴攻击行为精神分裂症患者认知功能的对照研究[J].中国行为医学科学,2006, 15(6):506-507.
[11] 周旭辉.酒精相关攻击行为的认知损害及神经生物学机制[C]//第四届中国酒精与药物滥用研讨会、第三届亚太酒精与成瘾学会会议论文集,2014:32-33.
[12] 穆殿萍.精神疾病患者暴力攻击行为原因分析及护理防范措施[J].继续医学教育,2016,1(1):120-121.
[13] Yoshikane F,Nozawa T,Tsuji K. Alcohol and suicide: a comparative analysis of France and Sweden [J]. Addiction,1995,90(11):1463.
[14] 范翔,刘筠,许亮,等.慢性酒精依赖患者脑结构改变的DKI研究[J].实用放射学杂志,2016,32(7):1005-1008.
[15] 许琼,郭建玲,徐翠华,等.酒精依赖患者同住家属的心理状况分析及护理干预措施[J].转化医学电子杂志,2016,3(11):77-78.
[16] 赵长江,余成新.酒精依赖者静息态脑功能磁共振成像研究进展[J].广东医学,2016,37(20):3139-3141.
[17] 穆喜术,李会,李淑芬,等.酒精依赖患者述情障碍的对照研究[J].医学研究与教育,2016,33(6):7-11,16.
[18] 郑珺珺.团体心理治疗对于酒精依赖患者的治疗体会[J].世界临床医学,2016,10(2):219.
[19] Zureik M,Ducimctiere P. High alcohol related premature mortality in France:concordant estimates from a prospective cohort study and national mortality statistics [J]. Alcohol Clin Exp Res,2010,20(3):428.
[20] 刘忠,李雅忠,王立娟,等.酒依赖患者系统综合治疗后不同时点复饮率调查[J].中国健康心理学杂志,2010, 18(8):913-915.