Abstract：Objective To observe the clinical efficacy of percutaneous kyphoplasty (PKP) in the treatment of osteoporotic multiple segmental thoracolumbar fractures in the elderly. Methods The clinical data of 46 patients with multi-segment senile osteoporotic vertebral fracture treated by PKP from April 2011 to January 2016 in Shaanxi Provincial People′s Hospital were retrospectively analyzed. Visual analogue scale (VAS), Oswestry disability index(ODI) score, vertebral body height, and vertebral Cobb angle were observed preoperatively at 3 days postoperatively and at the last follow-up, and the factors that affect postoperative efficacy were evaluated. Results PKP was performed on 113 vertebral lesions in 46 patients. The average cement injection volume was (4.05±1.20) mL. There was 11 vertebral cement leakages, including 1 nerve compression symptom and 7 cases were new-onset adjacent vertebral compressions fractures. The VAS scores, ODI scores at preoperative 3 d, the last follow-up and were compared, the differences were statistically significant (P < 0.01). The height of anterior vertebral body and vertebral body at the postoperative 3 d was significantly higher than before operation, and the height of the last follow-up was lower than the postoperative 3 d, the differences were statistically significant (P < 0.01). The Cobb angle at the postoperative 3 d was significantly lower than before opertation, and the Cobb angle of the last follow-up was higher than the postoperative 3 d, the differences were statistically significant (P < 0.01). Multivariate analysis found that bone density, the number of injured vertebrae, and adjacent vertebral fractures were related factors affecting surgical outcomes (P < 0.05). Conclusion PKP is a safe and effective method for the treatment of multi-segment senile osteoporotic thoracolumbar fractures. It can instantly reduce pain and improve quality of life.
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2018, Vol. 15 
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