Abstract:Objective To investigate the clinical effect of autologous bone graft combined with Bio-OSS bone meal in patients with bone defect after jaw cyst. Methods From March 2014 to December 2015, 60 patients with jaw cysts treated in the Department of Stomatology, the People′s Hospital Affiliated to Hubei Medical College were divided into control group (30 cases) and observation group (30 cases) by random number table. The control group was treated with Bio-OSS bone meal. The observation group was treated with autologous bone grafting on the basis of the control group. CT examination was performed at different time points before and after operation. The CT values and difference values in bone graft area were calculated, and the clinical efficacy and incision healing were compared. Results The healing rate in the observation group was better than that in the control group (P < 0.05). The CT values of the observation group were higher than those of the control group at 3, 6 and 9 months after operation (P < 0.05). The difference values of the observation group werre lower than those of the control group at 3, 6 and 9 months after operation (P < 0.05). Conclusion Autologous bone graft combined with Bio-OSS bone meal is effective in the postoperative bone defect of jaw cysts, which is helpful for incision healing and improving the CT value and difference value. It is worthy to be popularized.
余伟 向乐▲. 自体碎骨联合Bio-OSS骨粉应用于颌骨囊肿术后骨缺损中的临床效果[J]. 中国医药导报, 2017, 14(30): 129-131,135.
YU Wei XIANG Le▲. Clinical effect of autologous bone graft combined with Bio-OSS bone meal in bone defect after jaw cyst. 中国医药导报, 2017, 14(30): 129-131,135.
[1] 周俊波,马露,陈洁,等.牛骨粉(Bio-Oss)/人工生物膜(海奥)联合治疗下颌骨缺损骨腔的临床观察[J].口腔医学,2015,35(10):830-833.
[2] 岳喜龙,许胜,任光辉,等.上颌前牙区囊肿摘除术后Onlay植骨延期种植1例临床报告[J].中国实用口腔科杂志,2015,8(1):61-64.
[3] Tompkins M,Hamann JC,Diduch DR,et al. Preliminary results of a novel single-stage cartilage restoration technique:particulated juvenile articular cartilage allograft for chondral defects of the patella [J]. Arthroscopy,2013,29(10):1661-1670.
[4] 张璐,王频,郭玲,等.富自体浓缩生长因子纤维蛋白液在口腔骨缺损种植引导骨再生后的骨量变化[J].中国组织工程研究,2017,21(8):1186-1191.
[5] 杨立明,陈淑萍,李小菊,等. Bio-oss应用于种植牙唇侧骨缺损的锥形束CT研究[J].国际口腔医学杂志,2015, 42(4):420-422.
[6] 杜若鸿.开窗术及医用硫酸钙在中大型颌骨囊肿治疗中的应用及疗效评价[D].合肥:安徽医科大学,2013.
[7] 吴福雨,娄建军,孔春燕,等. Bio-oss骨粉单独应用于上前牙区缺损的影像学检查及修复效果评价[J].河北医药,2016,38(10):1515-1517.
[8] 蔺世晨,段少宇,朱静,等.浓缩生长因子联合骨代用品在上颌前牙区拔牙位点保存中的临床应用[J].首都医科大学学报,2017,38(3):451-456.
[9] Aly LA,Hammouda N. Secondary closure of alveolar cleft with resorbable collagen membrane and a combination of intraoral autogenous bone graft and deproteinized anorganic bovine bone:[J]. Ann Maxillofac Surg,2016,6(2):165-171.
[10] 王晓东,叶恒宇,王莉莉.显微根尖外科手术联合植骨术在治疗根尖周病变中的临床疗效观察[J].中华老年口腔医学杂志,2017,15(1):1-4.
[11] 牛志英,周朝宇,胡秋霞.前牙根端囊肿合并感染致骨缺损拔牙后位点保存的临床应用[J].口腔医学研究,2015, 31(4):413-414.
[12] Kim K,Lam J,Lu S,et al. Osteochondral tissue regeneration using a bilayered composite hydrogel with modulating dual growth factor release kinetics in a rabbit model [J]. J Control Release,2013,168(2):166-178.
[13] 韩尚哲,刘玉柱,胡青,等. Bio-Oss骨代用品混合自体骨碎屑移植在开窗法上颌窦底提升同期牙种植体植入术中的应用[J].解放军医药杂志,2016,28(1):82-84.
[14] 刘德裕,徐普,翦新春,等.富血小板纤维蛋白在即刻种植即刻负重骨缺损修复中的作用[J].中国现代医学杂志,2015,25(28):22-25.
[15] 谭鸾君,阮征,张劲娥,等. Bio-oss骨粉复合HIF-1α蛋白对拔牙创骨愈合影响的实验研究[J].口腔医学研究,2015,31(5):441-443.
[16] Akram M,Farooqi FM,Shahzad ML,et al. A comparison of treating unicameral bone cyst using steroids and percutaneous autologous bone marrow aspiration injection [J]. J Pak Med Assoc,2015,65(11 Suppl 3):S156.
[17] 杨立明,陈淑萍,李恩洪.浓缩生长因子(CGF)在即刻种植修复应用中的牙龈美学研究[J].中国美容医学杂志,2015,34(1):63-65.
[18] 杨芳,雷志敏,王林虎.微创拔牙后植入不同材料对牙槽窝保存技术的影响研究[J].中国美容医学杂志,2017, 26(2):102-104.
[19] 阮奕劲,石雄州,薛远琼,等.自体皮质骨外耳道上鼓室重建及骨粉乳突填塞在鼓室成形术中的应用[J].中国耳鼻咽喉头颈外科,2017,24(2):84-86.
[20] 王华,邓春富,张翀,等.胶原膜联合Bio-Oss骨粉成骨效果的实验研究[J].中国医科大学学报,2010,39(4):283-285.