Abstract:Objective To discuss the method that can improve the image quality of chest 18F-FDG SPECT coincidence imaging through analysis of the factors that affect the image quality. Methods The chest coincidence imaging of 100 patients in Beijing Chest Hospital, Capital Medical University from December 2016 to February 2017 were obtained. The imaging quality was classified as excellent in 12 cases, good in 72 cases and poor in 16 cases. The radioactivity counting and the standard deviation (SD) value of lung, chest wall, main vessel and liver were recorded. The relationship of subjective image quality and the objective value was analyzed. The patients' age, gender, height, body weight, blood glucose, injected FDG dose, check order, probe 1 and 2 of the radioactivity counting and coincidence rate, injection and scanning time interval were also recorded. The influences of above factors on image quality were analyzed. Results There was a significant difference of BMI, injected FDG dose of per kilogram body weight and the time interval between the injections and scan among the three groups (all P < 0.01). There was a significant difference in the radioactivity count of lung, chest wall, and liver among the three groups (all P < 0.01). There was a significant difference in SD value of the chest wall, large vessels and liver among the three groups (all P < 0.05). There was moderate correlation of the image quality and the coincidence rate (r = 0.505, P < 0.01), BMI was negatively correlated with image quality (r = -0.473, P < 0.01), while the injected FDG dose of per kilogram body weight was positively correlated with image quality (r = 0.343, P < 0.01). Conclusion The subjective image quality evaluation is in good agreement with the objective measured values. BMI is the most important factor that affects the image quality. The best dose of injected FDG and the appropriate injection and scanning time interval are beneficial to obtain the good quality image.
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