Abstract:Objective To investigate the effect of posterior pedicle screw fixation combined with internal bone graft in the treatment of thoracolumbar fracture. Methods From May 2015 to May 2017, 60 patients with thoracolumbar fracture in Department of Orthopedics, Qinghai Province People′s Hospital were selected, they were divided into posterior pedicle screw fixation combined with vertebral bone graft surgical group (study group, n = 30) and posterior vertebral pedicle screw fixation combined with posterolateral bone fusion group (control group, n = 30), according to surgical treatment methods, the vertebral anterior and posterior margin heights, cranial vertebral angle on the edge of the vertical and caudal vertebral edge vertical (Cobb angle), position of the sagittal diameter of the vertebral canal (Worter index), visual analogue scale (VAS) scores, intraoperation and postoperative indexes and clinical efficacy of the two groups were statistically analyzed. Results Compared with the control group, the height of the anterior and posterior margin of the injured vertebra in the study group were significantly higher, and the Cobb angle was significantly lower, the differences were statistically significant (P < 0.05). Compared with the control group, the Worter index and VAS score in the study group were significantly lower, the differences were statistically significant (P < 0.05). The length of incision, analgesic needle application time and hospitalization time, the intraoperative blood loss and postoperative drainage volume were significantly less than the control group, the differences were statistically significant (P < 0.05). The total treatment effective rate of the study group was significantly higher than the control group, the differences were statistically significant (P < 0.05). Conclusion The effect of posterior pedicle screw fixation combined with internal bone graft in the treatment of thoracolumbar fracture is better than posterolateral bone fusion, it can more effectively improve patients′ vertebral anterior and posterior height ratio, decrease patients′ Cobb angle, Worter index, VAS score, length of incision, shorten patients′ pain medication application time, hospitalization time, reduce patients′ intraoperative bleeding, postoperative drainage, improve patients′ total treatment efficiency.