Research progress on pathogenesis of atrial fibrillation
WANG Zengxia1 WANG He2 QIU Chengjie2 SI Chunying2 ZHAO Ya′nan1 GUAN Huaimin3 XIE Jinhong2
1.The First Shool Clinical Medicine, He′nan University of Chinese Medicine, He′nan Province, Zhengzhou 450000, China;
2.the Third Ward of Cardiovascular Medicine, the First Affiliated Hospital of He′nan University of Chinese Medicine, He′nan Province, Zhengzhou 450000, China; 3.Heart Center, the First Affiliated Hospital of He′nan University of Chinese Medicine, He′nan Province, Zhengzhou 450000, China
Abstract:Atrial fibrillation (AF) is the most common arrhythmia diagnosed in clinical practice. Now, precise mechanisms that lead to the onset and persistence of AF have not completely been elucidated. This paper mainly from the electrophysiological mechanisms of atrial fibrillation (including focal triggering mechanism, multiple wavelet hypothesis, etc.) and pathological physiological mechanism (electrical remodeling, contraction remodeling,structural remodeling, etc.) explain the possible pathogenesis of atrial fibrillation, in order to provide the basis or direction for the prevention and treatment of atrial fibrillation.
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