Research status of establishment of animal model of knee osteoarthritis
SONG Hanbing1 ZHAO Feng2 GE Yuanyuan2 YANG Dan2 YU Yingjun3▲
1.The Third Department of Orthopaedics, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Graduate School, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
3.School of Basic Medicine, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China
Abstract:Based on the continuous exploration on the fundamental researches of etiology and treatment mechanism of knee osteoarthritis, this paper takes in-depth analysis and finds that the animals used for establishing animal models with osteoarthritis at present are mainly rats and rabbits, the application of other animals, such as dogs, pigs, chickens and others, is less. The commonly model replicating methods are spontaneous models, operation models, and other methods, different animals and different methods have relatively strict distinction, so the choice of models should be based on the need of study.
宋寒冰1 赵峰2 葛圆圆2 杨丹2 于英君3▲. 膝关节骨性关节炎动物模型建立的研究现状[J]. 中国医药导报, 2017, 14(30): 46-49.
SONG Hanbing1 ZHAO Feng2 GE Yuanyuan2 YANG Dan2 YU Yingjun3▲. Research status of establishment of animal model of knee osteoarthritis. 中国医药导报, 2017, 14(30): 46-49.
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