原发性甲状腺淋巴瘤的超声表现特征分析

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摘要目的总结原发性甲状腺淋巴瘤（PTLs）各类型声像图特征，探讨其诊断及鉴别诊断要点。方法回顾性分析2008年8月—2019年5月于新疆医科大学附属肿瘤医院收治住院行术前超声检查后经穿刺活检或手术病理证实为PTLs患者65例，探讨其超声分型及声像图特征。结果 65例PTLs患者病灶中，39例（60.0%）为弥漫型，患者甲状腺不同程度肿大，包膜完整未被破坏，甲状腺实质回声弥漫性减低，呈不均匀性低回声至极低回声。所有弥漫型PTLs患者病灶内部均未见钙化及液化。28例（71.8%）患者病灶中可检出较丰富血流信号。22例（56.4%）中可见颈部淋巴结肿大。26例（40.0%）为非弥漫型，共47个病灶，其中11例为单发病灶，15例为多发病灶，16例（61.5%）为低回声，10例（38.5%）为极低回声。22例（84.6%）病灶形态不规则，低回声或极低回声病灶内可见多种形态中高回声，后方回声增强。19例（73.1%）患者病灶中可见丰富血流。19例（73.1%）中可见颈部淋巴结肿大。结论 PTLs具有一定的超声特征表现，必要时行穿刺活检或切取组织标本进行活检病理证实，以免误诊及漏诊。

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	张崴陈琦刘宏▲

关键词 ：甲状腺, 淋巴瘤, 病理诊断, 超声

Abstract：Objective To summarize the characteristics of each type of image for primary thyroid lymphomas (PTLs), and to discuss the diagnosis and differential diagnosis of PTLs. Methods From August 2008 to May 2019, a total of 65 patients with PTLs confirmed by biopsy or pathology after preoperative ultrasound examination were retrospectively analyzed. The ultrasonic classification and sonographic features were discussed. Results Of the 65 patients with PTLs, 39 cases (60.0%) were diffuse type. The thyroid gland was enlarged in varying degrees, the capsule was intact, and the echo of thyroid parenchyma was diffusely decreased, showing heterogeneous hypoechoic to extremely low echo. No calcification or liquefaction was found in the lesions of all patients with diffuse PTLs. Abundant blood flow signals were detected in 28 cases (71.8%). Cervical lymph node enlargement was found in 22 cases (56.4%). 26 cases (40.0%) were non diffuse type with 47 lesions, of which 11 cases were single lesion, 15 cases were multiple lesions, 16 cases (61.5%) were hypoechoic, and 10 cases (38.5%) were extremely hypoechoic. 22 cases (84.6%) had irregular shape, hypoechoic or extremely hypoechoic lesions. 19 cases (73.1%) had abundant blood flow. Cervical lymph node enlargement was found in 19 cases (73.1%). Conclusion PTLs have certain ultrasonographic features. If necessary, biopsy or biopsy should be performed to avoid misdiagnosis and missed diagnosis.

Key words： Thyroid Lymphoma Pathological diagnosis Ultrasound

基金资助:新疆维吾尔自治区自然科学基金资助项目（2017D01C394）。

通讯作者: ▲通讯作者

引用本文:

张崴陈琦刘宏▲. 原发性甲状腺淋巴瘤的超声表现特征分析[J]. 中国医药导报, 2020, 17(28): 144-146,164.
ZHANG Wei CHEN Qi LIU Hong▲. Analysis of ultrasonographic features of primary thyroid lymphomas. 中国医药导报, 2020, 17(28): 144-146,164.

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http://www.yiyaodaobao.com.cn/CN/ 或 http://www.yiyaodaobao.com.cn/CN/Y2020/V17/I28/144

[1] 夏宇，戴晴，姜玉新，等.原发甲状腺淋巴瘤的超声表现[J].中华超声影像学杂志，2010，19（2）：131-133.
[2] Derringer GA，Thompson LD，Erommeh RA，et al. Malignant lymphoma of the thyroid gland：a clinicopathologic study of 108 cases [J]. Am J Surg Pathol，2000，24（5）：623-639.
[3] Freeman C，Berg JW，Cutler SJ，et al. Occurrence and prognosis of extranodal lymphomas [J]. Cancer，1972，29（1）：252-260.
[4] Xia Y，Wang L，Jiang Y，et al. Sonographic appearance of primary thyroid lymphoma-preliminary experience [J]. PLoS One，2014，9（12）：114-118.
[5] Adler DD，Carson PL，Rubin JM，et al. Doppler ultrasound color flow imaging in the study of breast cancer：preliminary findings [J]. Ultrasound Med Biol，1990，16（6）：553-559.
[6] 赵佳琦，刁宗平，章建全，等.原发甲状腺淋巴瘤多种模式超声表现特征[J/CD].中华医学超声杂志：电子版，2017， 14（9）：701-705.
[7] Bostanci H，Dikmen K，Akyurek N，et al. Eleven patients with thyroid lymphma：a single center experience [J]. Turkish Medical Sci，2017，47（5）：1322-1327.
[8] Efstathios T，Pavlidis E，Pavlidis A，et al. Review of primary thyroid lymphoma：molecular factors，diagnosis and management [J]. Investig Surg，2017，18（6）：16.
[9] Yang L，Wang A，Zhang Y，et al. 12 cases of primary thyroid lymphoma in China [J]. Endocrinol Investig，2015，38（7）：739-744.
[10] Graff-Baker A，Roman SA，Thomas DC，et al. Prognosis of primary thyroid lymphoma：demographic，clinical，and pathologic predictors of survival in 1408 cases [J]. Surgery， 2009，146（6）：1105-1115.
[11] Alzouebi M，Goepel JR，Horsman JM，et al. Primary thyroid lymphoma：the 40 year experience of a UK lymphoma treatment centre [J]. Int J Oncol，2012，40（6）：2075-2080.
[12] Gokdogan O，Koybasiogu A，Ismail E，et al. Hoarseness：an unusual presentation of primary thyroid lymphoma with laryngeal infiltration [J]. Braz J Otorhinolaryngol，2016，82（6）：737-740.
[13] Widder S，Pasieka JL. Primary thyroid lymphomas [J]. Curr Treat Options Oncol，2004，5（4）：307-313.
[14] Sakorafas GH，Kokkoris P，Farley DR. Primary thyroid lymphoma（correction of lymphoma）：diagnostic and therapeutic dilemmas [J]. Surg Oncol，2010，19（4）：e124-e129.
[15] Takashima S，Morimoto S，Ikezoe J，et al. Primary thyroid lymphoma：comparison of CT and US assessment [J]. Radiology，1989，171（2）：439-443.
[16] Orita Y，Sato Y，Kimura N，et al. Characteristic ultrasound features of mucosa-associated lymphoid tissue lymphoma of the salivary and thyroid gland [J]. Acta Otolaryngol，2014，134（1）：93-99.
[17] 张秀梅，农琳，冉旭，等.甲状腺淋巴瘤临床病理及超声特征分析[J].中华医学杂志，2017，97（37）：2936-2939.
[18] Diaconescu M，Costea I，Glod M，et al. An unwonted clinicopathological subtype of thyroid primary lymphoma [J]. Chirurgia，2016，111（5）：428-431.
[19] 黄丽燕，黄小花，辜秋阳，等.原发性甲状腺淋巴瘤的超声分型与诊断分析[J].现代医药卫生，2018，23（12）：3669-3671.