Study on correlation between the quality of life of COPD patients and debilitating state
ZHOU Fujun1,2 CAO Cheng3 LIU Lei2 ZHU Min2 ZHU Hailan2 HONG Jingfang1
1.College of Nursing, Anhui Medical University, Anhui Province, Hefei 230032, China;
2.Department of Health and Nursing, Anhui Vocational College of City Management, Anhui Province, Hefei 230011, China;
3.Department of Thoracic Surgery, the Forth Affiliated Hospital of Anhui Medical University, Anhui Province, Hefei 230022, China
Abstract：Objective To study the correlation between the quality of life and the degree of degeneration of patients with chronic obstructive pulmonary disease (COPD), and to analyze the statistical correlation between the two to explore whether degeneration affects the quality of life of COPD patients. Methods The convenience sampling method was used to select 326 inpatients with COPD in the respiratory medicine department of a top three hospital from January to October 2019 as the research object, and the quality of life and the degree of degeneration were evaluated by the clinical COPD assessment test questionnaire (CAT) and the Tilburg frailty indicator scale (TFI). The impact of various indicators on quality of life was compared, while the correlation between the quality of life and the degree of weakness of COPD patients were analyzed. Results The differences in the CAT scores of COPD patients with different ages, financial burden, exercise time, body mass index, COPD grade, and number of complications were statistically significant (P ＜ 0.05). A total of 191 patients were found to be in a debilitating state, and the degeneration detection rate was 58.7%. Pearson correlation analysis showed that CAT scores was positively correlated with TFI total score (r = 0.484, P ＜ 0.01). The CAT score of COPD patients was related to TFI score (β [95%CI]: 1.021 [0.922, 1.120]). Conclusion The degree of degeneration of COPD patients will affect their quality of life, suggesting that improving degeneration in the treatment of COPD may be beneficial to the final recovery effect.
周福君1,2 曹成3 刘蕾2 朱敏2 朱海兰2 洪静芳1. COPD患者生活质量与衰弱状态的相关性研究[J]. 中国医药导报, 2020, 17(22): 17-20.
ZHOU Fujun1,2 CAO Cheng3 LIU Lei2 ZHU Min2 ZHU Hailan2 HONG Jingfang1. Study on correlation between the quality of life of COPD patients and debilitating state. 中国医药导报, 2020, 17(22): 17-20.
[1] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南（2017年修订版）[J].中华结核和呼吸杂志，2017（37）：4-15.
[2] Global Initiative for Chronic Obstructive Lung Disease（GOLD）. Global Strategy for the Diagnosis，Management，and Prevention of Chronic Obstructive Pulmonary Disease [updated-2016]. http：//goldCOPD.org/global-strategy-diagnosis-management-prevention-COPD-2016/.Accessed February 2，2016.
[3] Morley JE，Vellas B，van Kan GA，et al. Frailty consensus：a call to action [J]. J Am Med You Assoc，2013，14（6）：392-397.
[4] Ter Beek L，van der Vaart H，Wempe JB，et al. Coexistence of malnutrition，frailty，physical frailty and disability in patients with COPD starting a pulmonary rehabilitation program [J]. Clin Nutr，2019，16，pii：S0261-5614（19）33143-7.
[5] Park SK，Richardson CR，Holleman RG，et al. Frailty in people with COPD，using the National Health and Nutrition Evaluation Survey dataset（2003-2006）[J]. Heart Lung，2013，42（3）：163-170.
[6] Limpawattana P，Putraveephong S，Inthasuwan P，et al. Frailty syndrome in ambulatory patients with COPD [J]. Int J Chron Obstruct Pulmon Dis，2017，12：1193-1198.
[7] Marengoni A，Vetrano DL，Manes Gravina E，et al. The relationship between COPD and frailty：A systematic review and meta-analysis of observational studies [J]. Chest，2018，154（1）：21-40.
[8] 郝秋奎，李峻，董碧蓉，等.老年患者衰弱评估与干预中国专家共识[J].中华老年医学杂志，2017，36（3）：251-256.
[9] Gobbens RJ，van Assen MA，Luijkx KG，et al. The Tilburg Frailty Indicator：psychometric properties [J]. J Am Med Dir Assoc，2010，11（5）：344-355.
[10] Uchmanowicz I，Jankowska-Polańska B，Uchmanowicz B，et al. Validity and Reliability of the Polish Version of the Tilburg Frailty Indicator（TFI）[J]. J Frailty Aging，2016，5（1）：27-32.
[11] Mulasso A，Roppolo M，Gobbens RJ，et al. The Italian Version of the Tilburg Frailty Indicator：Analysis of Psychometric Properties [J]. Res Aging，2016，38（8）：842-863.
[12] Freitag S，Schmidt S，Gobbens RJ. Tilburg frailty indicator. German translation and psychometric testing [J]. Z Gerontol Geriatr，2016，49（2）：86-93.
[13] 奚兴，郭桂芳，孙静.中文版Tilburg衰弱评估量表的信效度研究[J].护理学报，2013，20（16）：1-5.
[14] Jones PW，Harding G，Berry P，et al. Development and first validation of the COPD Assessment Test [J]. Eur Respir J，2009，34（3）：648-654.
[15] Müllerová H，Dransfield MT，Thomashow B，et al. Clinical Development and Research Applications of the COPD Assessment Test（CAT）[J]. Am J Respir Crit Care Med，2019.
[16] 蔡睿，侯刚，王秋月，等.慢性阻塞性肺疾病评估测试对生存质量的评估价值研究[J].中国实用内科杂志，2011， 31（11）：847-849，901.
[17] Ierodiakonou D，Kampouraki M，Poulonirakis I，et al. Determinants of frailty in primary care patients with COPD：the Greek UNLOCK study [J]. BMC Pulm Med，2019，19（1）：63.
[18] Mitnitski AB，Graham JE，Mogilner AJ，et al. Frailty，fitness and late-life mortality in relation to chronological and biological age [J]. BMC Geriatr，2002，2（1）：1.
[19] Ma L，Zhang L，Tang Z，et al. Use of the frailty index in evaluating the prognosis of older people in Beijing：a cohort study with an 8-year follow-up [J]. Arch Gerontol Geriatr，2016，64：172-177.
[20] Chua JR，Albay Ab JR，Tee ML. Body Composition of Filipino Chronic Obstructive Pulmonary Disease（COPD）Patients in Relation to Their Lung Function，Exercise Capacity and Quality of Life [J]. Int J Chron Obstruct Pulmon Dis，2019，14：2759-2765.
[21] Finch S，Laska IF，Abo Leyah H，et al. Validation of the COPD Assessment Test（CAT）as an Outcome Measure in Bronchiectasis [J]. Chest，2019，pii：S0012-3692（19）34198-4.
[22] Zhang Y，Morgan RL，Alonso Coello P，et al. A systematic review of how patients value COPD outcomes [J]. Eur Respir J，2018，52（1）：1800222.
[23] Kessler R，Partridge MR，Miravitlles M，et al. Symptom variability in patients with severe COPD：a pan-European cross-sectional study [J]. Eur Respir J，2011，37（2）：264-272.
[24] Landis SH，Muellerova H，Mannino DM，et al. Continuing to Confront COPD International Patient Survey：methods，COPD prevalence，and disease burden in 2012-2013 [J]. Int J Chron Obstruct Pulmon Dis，2014，9：597-611.
[25] Maddocks M，Kon SS，Canavan JL，et al. Physical frailty and pulmonary rehabilitation in COPD：a prospective cohort study [J]. Thorax，2016，71（11）：988-995.
[26] Cesari M，Calvani R，Marzetti E. Frailty in Older Persons [J]. Clin Geriatr Med，2017，33（3）：293-303.
2020, Vol. 17 
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