Research progress of solomonseal rhizome treatment of cognitive impairment
WEI Ni′na1,2 XU Manman2 GAO Shaocai3 PAN Juhua2 HUANG Shijing2▲ WANG Yanyun2
1.Department of Traditional Chinese Medicine, the First Clinical Medical College, Shaanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China;
2.New Drug Research and Development Laboratory, Guang′anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China;
3.Department of Endocrine, Shaanxi Traditional Chinese Medicine Hospital, Shaanxi Province, Xi′an 710003, China
Abstract:This paper reviews the literature reports on pharmacological effects of solomonseal rhizome at home and abroad in recent years. The mechanism of action of solomonseal rhizome in the treatment of cognitive dysfunction is analyzed and summarized, it is concluded that solomonseal rhizome and its effective components and solomonseal rhizome compound preparations can effectively improve learning and memory ability of cognitively disabled organisms, alleviate the symptoms, such as insomnia, fatigue, forgetfulness, regulate the physiological and biochemical indexes, protect heart head blood-vessel, anti-inflammatory, anti-aging, improve immune function. It shows that solomonseal rhizome is effective in preventing and treating cognitive disorders, which can provide a reference for clinical prevention and treatment of cognitive dysfunction, and provide a new idea for the research and development of brain-strengthening and brain-beneficial new drugs.