Study on the characteristics of TCM syndrome of chronic cerebral circulatory insufficiency
LI Nannan1 CHEN Zhigang1 MENG Fanxing1 REN Shan1 CAI Yingli1 LI Xuejun1 LIU Jialin2
1.The Fisrt Department of Cerebropathy, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China;
2.Department of Neurosurgery, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China
Abstract：Objective To provide basis for TCM syndrome differentiation and treatment of chronic cerebral circulatory insufficiency through clinical observation of TCM syndrome distribution regularity and characteristics of patients suffering from chronic cerebral circulatory insufficiency. Methods All 76 patients with chronic cerebral circulatory insufficiency were the inpatients and outpatients of Dongfang Hospital of Beijing University of Chinese Medicine from January 2014 to January 2017. This paper clinically collected the TCM syndrome data about the patients with chronic cerebral circulatory insufficiency, developed the TCM syndrome observation scale, observed the TCM syndrome distribution regularity of 76 cases of patients with chronic cerebral circulatory insufficiency, input and analyzed the data, and explored the TCM syndrome distribution regularity of chronic cerebral circulatory insufficiency. Results ①In the 76 cases of patients with chronic cerebral circulatory insufficiency, the number of men was greater than women, and hypertensive disease accounted for the highest proportion in the concomitant underlying diseases, followed by dyslipidemia, diabetes, and coronary disease. ②Distribution of TCM syndrome factors: the common disease nature syndrome factors of the patients with chronic cerebral circulatory insufficiency included marrow deficient, phlegm turbidity, blood deficiency, qi deficiency and blood stasis; the common disease location syndrome factors included the brain, kidney and liver. In the complicated situation of all syndrome factors of patients with chronic cerebral circulatory insufficiency, there were only 4 cases (5.3%) with single symptom, and 65 cases (85.5%) with 2-4 symptoms. There were 29 cases (38.2%) with pure deficiency syndrome, only 1 case (1.3%) with pure excess syndrome, and 46 cases (60.5%) with the syndrome of intermingled deficiency and excess. ③A cluster analysis of 9 disease nature syndrome factors was made; when clustered into two categories, phlegm turbidity and marrow deficiency was classified as category Ⅰ, and other 7 symptoms were classified as category Ⅱ. ④The correlation between the disease nature syndrome factors of chronic cerebral circulatory insufficiency patients and the concomitant underlying diseases was analyzed respectively, and the results showed that the blood stasis showed a positive correlation with dyslipidemia (P ＜ 0.05); phlegm turbidity syndrome was positively correlated with hypertension (P ＜ 0.05). But, there was no significant correlation between other syndrome factors and underlying diseases (P ＞ 0.05). Conclusion Chronic cerebral circulatory insufficiency is a kind of disease intermingled deficiency and excess, with vital energy deficiency, blood deficiency, marrow deficiency and etc. as the root causes, and phlegm turbidity and blood stasis as the manifestations; the syndrome of phlegm turbidity and marrow deficiency in the patints suffering form chronic cerebral circulatory insufficiency complicated with atherosclerotic stenosis is more apparent. The pathogenesis of chronic cerebral circulatory insufficiency is complex, the main syndrome is intermingled deficiency and excess.
李楠楠1 陈志刚1 孟繁兴1 任珊1 蔡英丽1 李学军1 刘佳霖2. 慢性脑供血不足中医证候学特点研究[J]. 中国医药导报, 2018, 15(36): 135-139.
LI Nannan1 CHEN Zhigang1 MENG Fanxing1 REN Shan1 CAI Yingli1 LI Xuejun1 LIU Jialin2. Study on the characteristics of TCM syndrome of chronic cerebral circulatory insufficiency. 中国医药导报, 2018, 15(36): 135-139.
2018, Vol. 15 
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