Abstract：Objective To explore the mediating effects of coping strategies in the relationship between stress reaction, coping strategies and infertility with infertility-related stress in infertile women of advanced reproductive age already have one child. Methods The study was conducted in 1360 women of advanced reproductive age who were planned second child, initially diagnosed with infertility in Reproductive Medical Center of Cangzhou Hospital of Integrated TCM-WM from January 2016 to June 2017. Self-made questionnaires was used for selected patients basic information survey. Stress reaction questionnaire, coping strategies questionnaire and fertility problem inventory were used to analyze the relationship between stress reaction, coping strategies and infertility-related stress, and the mediating effects of positive and negative coping strategies on infertility-related stress in infertile women of advanced reproductive age. Results There was a positive correlation between stress reaction questionnaire score and all dimensions of the infertility - related stress score and its total score (P < 0.05). In addition to the need for parenthood, the score of positive coping strategies was negatively correlated with the score of the infertility-related stress score and its total score (P < 0.05). The score of negative coping strategies was positively correlated with the score of the infertility-related stress score and its total score (P < 0.05). The structural equation of stress response, positively related with pressure and fertility pressure was ideal, and the mediating effect of positive coping strategies on infertility - related stress was significant (P < 0.05). The structural equation of stress response, negative response to pressure and fertility pressure was relatively ideal, but the mediating effect of positive coping strategies on infertility - related stress was not significant (P > 0.05). Conclusion The effect of stress response on positive response to pressure and negative response to pressure can affect the infertile women of advanced reproductive age already have one child. The mediating effect of positive coping strategies is significant.
2018, Vol. 15 
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