A case of tri-allele in TPOX was detected using Goldeneye 20A Kit for the first time
ZHOU Danhua1,2* HU Xijie1,2* ZHANG Tao1,2 WAN Weihong1,2 YU Jian2 LIU Zulin1,2 YU Limei1,2
1.Key Laboratory of Cell Engineering in Guizhou Province, Guizhou Province, Zunyi 563003, China;
2.Centre of Forensic Medicine, the Affiliated Hospital of Zunyi Medical University, Guizhou Province, Zunyi 563003, China
Abstract：This article reports one case of tri-allele detected in the TPOX locus of a child in duos. The Goldeneye 20A kit was used for detecting. The 3500DX genetic analyzer was used for electrophoresis and Genemapper genotyping software was used confirm its genotyping (8, 9, 11). When the tri-allelic gene is detected in the paternity test, under the premise of eliminating contamination, at least two kits are required to confirm the test to ensure the reliability of the identification and PI calculation. In order to improve the accuracy of the case report, the tri-allele test, the peak type analysis, the classification and judgment and the confirmation should be handled with care so that provides basic information for the analysis of the possible mechanisms of tri-allele.
周单华1,2* 胡锡阶1,2* 章涛1,2 万卫红1,2 余舰2 刘祖林1,2 余丽梅1. Goldeneye 20A试剂盒检测发现TPOX基因座三等位基因一例[J]. 中国医药导报, 2018, 15(14): 146-148.
ZHOU Danhua1,2* HU Xijie1,2* ZHANG Tao1,2 WAN Weihong1,2 YU Jian2 LIU Zulin1,2 YU Limei1,2. A case of tri-allele in TPOX was detected using Goldeneye 20A Kit for the first time. 中国医药导报, 2018, 15(14): 146-148.
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2018, Vol. 15 
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